Development of treatment method for the prevention of dental caries and dentin hypersensitivity with ammonium hexafluorosilicate

六氟硅酸铵预防龋齿和牙本质过敏的治疗方法的开发

• 批准号: 19592203
• 负责人: SUGE Toshiyuki
• 金额: $ 2.83万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19592203/
• 关键词: 象牙質知覚過敏症; 齲蝕; フッ素; フッ化ジアミンシリケート; アパタイト; エナメル質; シリカ; フッ化ジアンミン銀; フッ化カルシウム; 象牙細管; 抗菌成分

Diamine silver fluoride (Saforide) is clinical use for prevent of progress of dental caries and desensitizing for hypersensitive tooth. Unfortunately, diamine silver fluoride stained tooth black due to silver precipitation. To overcome this drawback, ammonium hexafluorosilicate was prepared. The purpose of this study was to evaluate the occluding ability of dentin tubules and acid resistance of bovine tooth after ammonium hexafluorosilicate treatment. It was concluded that ammonium hexafluorosilicate is useful for the treatment of dentin hypersensitivity and prevent of progress of dental caries since ammonium hexafluorosilicate treatment occluded open dentin tubules completely with silica-calcium phosphate precipitate and increased acid resistance of bovine tooth without changing the color of tooth.

二胺银氟化物（Saforide）是临床上用于预防龋齿的进展和脱敏过敏牙。不幸的是，由于银沉淀，二胺银氟化物将牙齿染黑。为了克服这个缺点，制备了六氟硅酸铵。本研究的目的是评价牛牙经六氟硅酸铵处理后，牙本质小管的封闭能力和抗酸能力。结果表明，氟硅酸铵能使牙本质小管完全封闭，使牙本质小管中的硅钙磷酸盐沉淀物完全封闭，并能提高牛牙的抗酸能力，对牙本质过敏症的治疗和龋病的预防有一定的作用。

项目成果

保存修復学専門用語集

保护和恢复术语词汇表

• 发表时间: 2009
• 作者: Inuyama Y;Kitamura C;Ishimatsu H;Morotomi T;Nagayoshi M;Nishihara T;Terashita M;諸冨孝彦;犬山喜夫,北村知昭,諸冨孝彦,永吉雅人,寺下正道;諸冨孝彦,北村知昭,寺下正道;石松宏隆,北村知昭,諸冨孝彦,田畑泰彦,寺下正道;Inuyama Y.;諸冨孝彦;諸冨孝彦;諸冨孝彦;犬山喜夫;石松宏隆;石松宏隆;犬山喜夫;犬山喜夫;石松宏隆;諸冨孝彦,坂本英治,北村知昭,椎葉俊司,矢野淳也,永吉雅人,仲西修,寺下正道;吉田真理,藤本陽子,北村知昭,永吉雅人,諸冨孝彦,波多野圭紀,寺下正道;有田正博,陳克恭,芳賀健輔,小城辰郎,松木貴彦,中村恵子,波多野圭紀,矢野淳也,諸冨孝彦,笠井宏記,永吉雅人.;諸冨孝彦,坂本英治,北村知昭,椎葉俊司,矢野淳也,永吉雅人,寺下正道;坂本英治,諸冨孝彦,北村知昭,椎葉俊司,矢野淳也,永吉雅人,寺下正道,仲西修;寺下正道,北村知昭,諸冨孝彦,他
• 通讯作者: 寺下正道,北村知昭,諸冨孝彦,他