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Studies of genomics and proteomics for pathologic factors in temporomandibular joint

Studies of genomics and proteomics for pathologic factors in temporomandibular joint
颞下颌关节病理因素的基因组学和蛋白质组学研究
批准号:
19592318
负责人:
KONDOH Toshirou
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
Synovitis that often accompanies intracapsular pathologic conditions is characterized by chronic inflammatory changes in the temporomandibular joint (TMJ). We have investigated of IL-1β or TNF-α-responsive genes in synoviocytes for putative genes associated with the synovitis using microarray analysis because IL-1b and TNF-a elevated in synovial fluids obtained from TMJ with pathologic conditions. Then, the protein levels of IL-1β or TNF-α-responsive factors have been investigated in synovitis models in vitro and in vivo.
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会议论文
Study of inflammasome and molecular process of inflammation in temporomandibular joint
  • 批准号:
    16K11704
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.08万
  • 财政年份:
    2016
  • 负责人:
    KONDOH Toshirou
  • 依托单位:
Analysis of inflammatory network and molecularly-targeted therapy in tempromandibular joint inflammation
  • 批准号:
    25463099
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.24万
  • 财政年份:
    2013
  • 负责人:
    KONDOH Toshirou
  • 依托单位:
Analysis of microRNA in temporomandibular joint inflammation
  • 批准号:
    22592230
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2010
  • 负责人:
    KONDOH Toshirou
  • 依托单位:
Establishment for diagnostic arthroscopy into lower joint compartment of the temporomandibular joint by newly developed thin diameter arthroscope system
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