Studies of genomics and proteomics for pathologic factors in temporomandibular joint
Studies of genomics and proteomics for pathologic factors in temporomandibular joint
批准号:
19592318
负责人:
KONDOH Toshirou
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
Synovitis that often accompanies intracapsular pathologic conditions is characterized by chronic inflammatory changes in the temporomandibular joint (TMJ). We have investigated of IL-1β or TNF-α-responsive genes in synoviocytes for putative genes associated with the synovitis using microarray analysis because IL-1b and TNF-a elevated in synovial fluids obtained from TMJ with pathologic conditions. Then, the protein levels of IL-1β or TNF-α-responsive factors have been investigated in synovitis models in vitro and in vivo.
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会议论文
Study of inflammasome and molecular process of inflammation in temporomandibular joint
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批准号:16K11704
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2016
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负责人:KONDOH Toshirou
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依托单位:
Analysis of inflammatory network and molecularly-targeted therapy in tempromandibular joint inflammation
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批准号:25463099
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2013
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负责人:KONDOH Toshirou
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依托单位:
Analysis of microRNA in temporomandibular joint inflammation
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批准号:22592230
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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负责人:KONDOH Toshirou
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依托单位:
Establishment for diagnostic arthroscopy into lower joint compartment of the temporomandibular joint by newly developed thin diameter arthroscope system
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批准号:12671974
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2000
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负责人:KONDOH Toshirou
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依托单位:
海外基金