Induction of bioactivity on organic polymeric materials by cluster ion beams

簇离子束诱导有机聚合物材料生物活性

• 批准号: 19680027
• 负责人: KAWASHITA Masakazu
• 金额: $ 15.39万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (A)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19680027/
• 关键词: クラスターイオンビーム; 生体活性; アパタイト; 擬似体液; 有機高分子; 表面改質; 官能基; 親疎水性; シリコーンゴム; 高分子

Silicone elastomer or polyethylene substrates were irradiated under various conditions by the simultaneous use of oxygen cluster and monomer (O_2CM) ion beams, and then soaking in CaCl_2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF).The hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O_2CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer or polyethylene substrates.

用氧团簇和单体(O_2 Cm)离子束在不同条件下辐照有机硅弹性体或聚乙烯基片，然后浸泡在CaCl2溶液中。用离子浓度是正常模拟体液(1.5SBF)的1.5倍的亚稳磷酸钙溶液检测了基质的磷灰石形成能力，辐照显著提高了基质的亲水性。辐照后的衬底在1.5SBF下形成磷灰石，而未辐照的衬底则没有。这些结果表明，用O_2 cm离子束辐照可以有效地诱导硅橡胶或聚乙烯衬底上形成磷灰石。

项目成果

Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams

氧簇和单体离子束同时照射诱导有机硅弹性体生物活性

• 发表时间: 2009
• 期刊: Acta Biomaterialia 5
• 作者: Sato K;Arai H;Miyazawa Y;Fukaya M;Uebanso T;Koganei M;Sasaki H;Sato T;Yamamoto H;Taketani Y;Takeda E.;M.Kawashita
• 通讯作者: M.Kawashita

In vitro apatite formation on polymer substrates irradiated by the simultaneous use of oxygen cluster and monomer ion beams

同时使用氧簇和单体离子束照射聚合物基底上的体外磷灰石形成

• 发表时间: 2007
• 期刊: Mater. Res. Soc. Symp. Proc. 1020
• 作者: M.Han;N.Nishiyama;et al.;M. Kawashita
• 通讯作者: M. Kawashita

Apatite formation on silicone substrates irradiated by cluster ion beams

簇离子束辐照下硅基底上磷灰石的形成

• 发表时间: 2007
• 作者: H. Cabral;N. Nishiyama;et.al.;M. Kawashita
• 通讯作者: M. Kawashita

Effect of ion species on apatite-forming ability of silicone elastomer substrates irradiated by cluster ion beams

离子种类对簇离子束辐照有机硅弹性体基体磷灰石形成能力的影响

• 发表时间: 2009
• 期刊: Mater. Sci. Engin. B 161
• 作者: M. Kawashita;R. Araki;G.H. Takaoka
• 通讯作者: G.H. Takaoka

Effect of ion species on apatite-forming ability of silicone substraes irradiated by cluster ion beams

离子种类对团簇离子束辐照有机硅基体磷灰石形成能力的影响

• 发表时间: 2008
• 作者: M. Kawashita;R. Araki;G.H. Takaoka
• 通讯作者: G.H. Takaoka