Induction of bioactivity on organic polymeric materials by cluster ion beams

用氧团簇和单体(O_2 Cm)离子束在不同条件下辐照有机硅弹性体或聚乙烯基片，然后浸泡在CaCl2溶液中。用离子浓度是正常模拟体液(1.5SBF)的1.5倍的亚稳磷酸钙溶液检测了基质的磷灰石形成能力，辐照显著提高了基质的亲水性。辐照后的衬底在1.5SBF下形成磷灰石，而未辐照的衬底则没有。这些结果表明，用O_2 cm离子束辐照可以有效地诱导硅橡胶或聚乙烯衬底上形成磷灰石。

Silicone elastomer or polyethylene substrates were irradiated under various conditions by the simultaneous use of oxygen cluster and monomer (O_2CM) ion beams, and then soaking in CaCl_2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF).The hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O_2CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer or polyethylene substrates.