Induction of bioactivity on organic polymeric materials by cluster ion beams

用氧簇和单体离子束（O_2CM）同时辐照硅橡胶或聚乙烯基片，然后浸泡在CaCl_2溶液中。采用离子浓度为1.5倍正常模拟体液（1.5SBF）的亚稳磷酸钙溶液，考察了衬底的磷灰石形成能力，发现衬底的亲水性得到了显著改善。照射基板形成磷灰石在1.5SBF，而未照射的没有。这些结果表明，用O_2CM离子束辐照可有效地诱导硅橡胶或聚乙烯衬底上的磷灰石形成能力。

Silicone elastomer or polyethylene substrates were irradiated under various conditions by the simultaneous use of oxygen cluster and monomer (O_2CM) ion beams, and then soaking in CaCl_2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF).The hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O_2CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer or polyethylene substrates.