课题基金 / 基金详情

Translational research of animal study and clinical trial for the mechanisms of weather-dependent pain aggravation.

Translational research of animal study and clinical trial for the mechanisms of weather-dependent pain aggravation.
天气依赖性疼痛加重机制的动物研究和临床试验的转化研究。
批准号:
20390415
负责人:
SATO Jun
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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项目成果

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中文摘要
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英文摘要
The authors have clarified underlying mechanisms of weather-sensitive diseases, such as chronic pain and depression in the basic animal research. In the present research project, we have further progressed the animal study and had clinical study using chronic pain patients with their pain to be sensitive to weather change. This translational study succeeded to product human model of weather-sensitive pain and provided a scientific link between laboratory research and human trials, and the beginning of discovery of therapeutic strategies for this syndrome.
期刊论文(0)
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会议论文
Increases in neuronal activity in rat spinal trigeminal nucleus following changes in barometric pressure-relevance for weather-associated headache
气压变化导致大鼠三叉神经脊髓神经元活动增加,与天气相关的头痛相关
DOI: --
发表时间: 2010
期刊: Headache Vol.50, No.9
影响因子: --
作者: [MESSLINGER Karl, FUNAKUBO Megumi, SATO Jun, MIZUMURA Kazue]
通讯作者: MIZUMURA Kazue
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kiya T, Kawamarta T, Yamakage M, 大宮康次郎]
通讯作者: 大宮康次郎
気象病における自律神経系の関与
自主神经系统与气象疾病的关系
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [松井博, 他(全8名), 佐藤純]
通讯作者: 佐藤純
Lowering barometric pressure aggravates anxiety/depression-like behavior in rats
降低气压会加剧大鼠的焦虑/抑郁样行为
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Suehiro A., Hirano S., Kishimoto Y., Rousseau B., Nakamura T., Ito J., 佐藤純]
通讯作者: 佐藤純
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