The influence of the sympathetic nerve system on the differentiation and pain of the masticatory muscles

交感神经系统对咀嚼肌分化及疼痛的影响

• 批准号: 22592203
• 负责人: SATO Jun
• 金额: $ 2.83万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592203/
• 关键词: 咀嚼筋; 筋痛; 口腔顎顔面痛; 交換神経系; 顎顔面痛; 交感神経; 顎関節症

The number of the patient with recurrent chronic orofacial pain is increasing. The main pathophysiology of the patients with chronic orofacial pain is muscle pain. We studied the relationships between the activities of sympathetic nerve system or influence of soft-diet and the differentiation or metabolic activities of the muscle fibers in the masticatory muscles. The animal experiences of the rabbit indicated that sympathetic nerve system may affect the differentiation or metabolic activities of the muscle fibers in the masticatory muscles. Moreover, necrosis of the muscle fibers of the side of sympathectomy might indicate the correlation with occurrence of the diseases such as muscular dystrophy. Another animal experience with growing rabbit indicated that soft-diet habit may also contribute to the differentiation or metabolic activities of the muscle fibers in the masticatory muscles. Clinical studies indicated that stimulation and inhibition of the sympathetic nerve system may affect the threshold of the pressure pain of the masticatory muscles. The degrees of the change of the threshold of the pressure pain of the muscles may depend on the pain of the orofacial region.

复发性慢性口面部疼痛患者的数量正在增加。慢性口面部疼痛患者的主要病理生理是肌肉疼痛。本实验研究了咀嚼肌交感神经系统的活动和软食的影响与肌纤维分化和代谢活动的关系。动物实验表明，交感神经系统可能影响咀嚼肌纤维的分化和代谢活动。此外，交感神经切除侧的肌纤维坏死可能与肌营养不良症等疾病的发生有关。另一项生长兔的动物实验表明，软饮食习惯也可能有助于咀嚼肌肌纤维的分化或代谢活动。临床研究表明，交感神经系统的兴奋和抑制可影响咀嚼肌的压痛阈值。肌肉压痛阈值变化的程度可能取决于口面部疼痛。

项目成果

Unique characteristics of the masseter muscle in patient with jaw deformity

颌畸形患者咬肌的独特特征

• 发表时间: 2012
• 作者: Yoshimasa Kitagawa;Jun Sato
• 通讯作者: Jun Sato

開口障害の精査依頼で受診した破傷風の1例

拜访一例破伤风患者，对牙关紧闭进行详细检查。

• 发表时间: 2010
• 作者: 佐藤淳、北川善政;ら;佐藤淳;今井弘一;阿部貴洋,佐藤淳
• 通讯作者: 阿部貴洋,佐藤淳

成長期のsoftdietがウサギの咬筋および内・外側翼突筋におよぼす影響について

生长期间软食对兔咬肌和翼内肌和翼外肌的影响

• 发表时间: 2010
• 作者: 今井弘一;武田昭二;佐藤淳
• 通讯作者: 佐藤淳

成長期のsoft dietがウサギの咬筋および内・外側翼突筋におよぼす影響について

生长期间软食对兔咬肌和翼内肌和翼外肌的影响

• 发表时间: 2010
• 作者: 佐藤淳、北川善政;ら
• 通讯作者: ら

Ring fibers visualized by electron microscopy in a Japanese patient with malignant hyperthermia

通过电子显微镜观察一名日本恶性高热患者的环形纤维

• 发表时间: 2011
• 期刊: Odontology
• 影响因子: 2.5
• 作者: Yoshimasa Kitagawa;Jun Sato;Masaru Kuriyama;Kazuo Sano;Kenji Hashimoto
• 通讯作者: Kenji Hashimoto