Developing new treatment modalities of urothelial carcinoma through regulating microRNA expression
Developing new treatment modalities of urothelial carcinoma through regulating microRNA expression
批准号:
20390427
负责人:
NAKAGAWA Masayuki
金额:
$12.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We screened 667 microRNAs in urothelial carcinoma specimens and identified the profile of down-regulated miRNAs, such as miR-1, miR-133a, and miR-145, which have tumor suppressive function. These miRNAs directly repressed the expression levels of novel oncogenic genes, such as FSCN1, LASP1, and GSTP1. On the other hand, miR-96 and miR-183, which were the top two up-regulated miRNAs in the profile, were subjected to tests for evaluating their ability as urine markers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1038/sj.bjc.6605990
发表时间:
2011-01-18
期刊:
British journal of cancer
影响因子:
8.8
作者:
[]
通讯作者:
DOI:
10.3892/ijo.2011.1012
发表时间:
2011-07-01
期刊:
INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子:
5.2
作者:
[Tatarano, Shuichi, Chiyomaru, Takeshi, Nakagawa, Masayuki]
通讯作者:
Nakagawa, Masayuki
MicroRNAs (miR-96 and miR-183) detection serves as urine markers in patients with urothelial carcinoma
MicroRNA(miR-96 和 miR-183)检测可作为尿路上皮癌患者的尿液标记物
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Chiyomaru T, Enokida H, Enokida H]
通讯作者:
Enokida H
染色体構造異常解析に基づいた膀胱癌における腫瘍抑制的なmicroRNAの同定
基于染色体结构畸变分析鉴定膀胱癌中的抑癌microRNA
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ko jima S, et al., 千代丸剛, 鑪野秀一]
通讯作者:
鑪野秀一
microRNA発現プロファイリングに基づく膀胱癌の検出方法
基于microRNA表达谱的膀胱癌检测方法
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 31 条
Elucidating anticancer drug resistance in urothelial carcinoma by multi-faceted approach
-
批准号:19K09715
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2019
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Verification of Time Consistency Conditions for Pre-Disaster Prevention Measures and Post-Disaster Relief and Reconstruction Projects
-
批准号:18H03639
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$28.04万
-
财政年份:2018
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Exploring molecular network of functional nucleic acid and developing therapeutic innovations in drug-resistant renal cell carcinoma
-
批准号:16H05464
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2016
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Rethinking of City Planning Law by Econimics
-
批准号:21330068
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2009
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Prediction of prognosis and clinical application of gene methylation score in urothelial cancers
-
批准号:18591761
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.51万
-
财政年份:2006
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Efficiency Analysis of Economic Planning Policy : Feasibility Studies of Experimental and Empirical Method
-
批准号:17203023
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.29万
-
财政年份:2005
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Establishment of prediction system for the prognosis of patients with bladder cancer
-
批准号:16591603
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2004
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Analysis of Low Level Living in Japan Using Audit Study
-
批准号:13630054
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.79万
-
财政年份:2001
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Role of tumor-associated macrophage in tumor invasion and inhibition of tumor invasion in urothelial cancers
-
批准号:12671546
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2000
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Typological Cognitive Study of Grammatical Discrepancy between Kango and Original Chinese
-
批准号:11610466
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.45万
-
财政年份:1999
-
负责人:NAKAGAWA Masayuki
-
依托单位:
STUDY ON MECHANISM OF TUMOR ANGIOGENESIS IN UROTHELIAL CANCERS AND SCREENING OF ANGIOGENIC INHIBITORS
-
批准号:07671739
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1995
-
负责人:NAKAGAWA Masayuki
-
依托单位:
STUDIES ON MECHANISMS OF CISPLATINUM-RESISTANCE IN URINARY TUMORS AND DRUG SCREENING FOR REVERSAL OF THE RESISTANCE.
-
批准号:05671326
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1993
-
负责人:NAKAGAWA Masayuki
-
依托单位:
Investigation and Analyze of Language feed-back of Chinese learners.
-
批准号:59310062
-
项目类别:Grant-in-Aid for Co-operative Research (A)
-
资助金额:$4.42万
-
财政年份:1984
-
负责人:NAKAGAWA Masayuki
-
依托单位:
国内基金
海外基金
登录
查看更多内容
AKR1C1抑制铁死亡途径调节膀胱尿路上皮癌中维迪西妥单抗治疗的敏感性研究
-
批准号:2026JJ81335
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:王晶晶
-
依托单位:
冷冻消融介导肿瘤相关巨噬细胞代谢重编程强化上尿路尿路上皮癌免疫治疗敏感性的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:陈艺凌
-
依托单位:
恶性肿瘤精准诊治新技术和新策略研究-新型基于Nectin-4靶点CAR-NK细胞疗法的开发及其治疗晚期尿路上皮癌的应用研究
-
批准号:2025C02072
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:黄航
-
依托单位:
TGFB1诱导CAFs细胞分化通过T细胞耗竭导致尿路上皮癌不良预后的机制研究
-
批准号:JCZRLH202501210
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
恶性肿瘤精准诊治新技术和新策略研究-基于尿液多组学联合AI多模态影像组学的尿路上皮癌早筛早诊新技术体系构建
-
批准号:2025C02058
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:丁国庆
-
依托单位:
基于二元视角的膀胱高级别尿路上皮癌患者参与治疗决策干预方案的构建与应用
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:童丹丹
-
依托单位:
基于多组学的尿路上皮癌精准诊断体系建立及复发监测技术研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:陈伟
-
依托单位:
长链非编码RNA HOTAIR通过HMGB1调节自噬影响膀胱尿路上皮癌顺铂化疗敏感性的作用及机制研究
-
批准号:2025JJ80151
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:黄智超
-
依托单位:
新型光动力纳米siRNA载体靶向抑制P3H4基因治疗膀胱尿路上皮癌的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:张前进
-
依托单位:
CDKL1 参与膀胱尿路上皮癌患者预后和肿瘤细胞代谢的机制研究
-
批准号:2024JJ7665
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:杨帆
-
依托单位: