Titanium implant surface modification and tissue regeneration by phosphorylated pullulan

磷酸化普鲁兰多糖对钛种植体表面修饰及组织再生

• 批准号: 20390498
• 负责人: SUZUKI Kazuomi
• 金额: $ 12.23万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390498/
• 关键词: インプラント; チタン; 表面処理; 骨伝導; 上部構造体; 適合性; 接着材; 被膜強さ; 被膜厚さ

The improvement of bone formation-inducing activity for dental implant treatment and the newly developed adhesive for superstructure (crown, bridge, etc) were investigated. At 2 weeks after the implant surgery in rat tibia, the enhanced new bone formation was showed on the titanium surface treated with phosphorylated pullulan. The bone strength to Ag-Au-Pt-Cu alloys of 15-20% derivatized amino acid (cystine) containing urethane dimethacrylate polymers was 22.4MPa(SD:1.8),and the degradation of the bone strength was only 10% after thermal cycling with 20.000 cycles at 5-55℃.

对种植体治疗中骨形成诱导活性的提高及上部结构（牙冠、牙桥等）的新型粘接剂进行了研究。大鼠胫骨植入术后2周，磷酸化普鲁兰处理后钛表面新骨形成增强。15-20%衍生化氨基酸（胱氨酸）含氨基二甲基丙烯酸酯聚合物对Ag-Au-Pt-Cu合金的骨强度为22.4MPa(SD:1.8)，在5-55℃下进行20000次热循环后，骨强度仅下降10%。

项目成果

Mechanical properties of resin-modified glass ionomer cements for luting : Effect of adding spherical silica filler.

用于粘合的树脂改性玻璃离子水门汀的机械性能：添加球形二氧化硅填料的影响。

• 发表时间: 2010
• 期刊: Dental Materials Journal 29
• 作者: Lihua;E.;Irie;M.;Nagaoka;N.;Yamashiro;T.;Suzuki;K.
• 通讯作者: K.

Determinants of early interfacial-gap performance of indirect composite restoration.

间接复合修复体早期界面间隙性能的决定因素。

• 发表时间: 2010
• 期刊: Dental Materials 26
• 作者: Irie;M.;Maruo;Y.;Nishigawa;G.;Suzuki;K.;Watts;D.C.
• 通讯作者: D.C.

Flexral performance of flowable versus conventional light-cured composite resin in long-term in vitro study.

长期体外研究中可流动复合树脂与传统光固化复合树脂的弯曲性能。

• 发表时间: 2008
• 期刊: Dental Materials Journal 27
• 作者: Irie;M.;Tjandrawinata;R.;Lihua;E.;Suzuki;K.
• 通讯作者: K.

Early No Interfacial-Gap Incidence vs. Flexural Modulus with Injectable Composites

可注射复合材料的早期无界面间隙发生率与弯曲模量

• 发表时间: 2011
• 作者: Irie M;Tamada Y;Maruo Y;Nishigawa G;Oka M;Minagi S;Sazuki K;Watts DC
• 通讯作者: Watts DC

Fiexral Performance of Flowable versus Conventional Light-cured Composite Resins in a Long-term in vitro Study

长期体外研究中可流动复合树脂与传统光固化复合树脂的固定性能

• 发表时间: 2008
• 期刊: Dental Materials Journal 27
• 作者: Irie;M.;et al.
• 通讯作者: et al.