Molecular patho-epidemiological study on oral superficial carcinoma in East Asia regions

东亚地区口腔浅表癌分子病理流行病学研究

• 批准号: 20406029
• 负责人: CHENG Jun
• 金额: $ 10.73万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20406029/
• 关键词: 口腔がん; 表在性癌; 発症機構; 病理疫学; 分子病理学; 扁平上皮癌; 病理組織学; 免疫組織化学

Oral cancers, especially superficial carcinomas, are increasing in number not only in Japan but also Asian countries, which seems to be in parallel to changing of those countries into aging societies. Epidemiologically and molecular pathologically comparing Japanese cases and East Asian cases, we have shown that oral superficial carcinoma is a lesional complex of borderline malignancies including from epithelial dysplasia to micro-invasive carcinoma by establishing pathological diagnostic criteria for carcinoma in-situ, which were biological evidence-based.

口腔癌，特别是浅表癌，不仅在日本，而且在亚洲国家的数量也在增加，这似乎与这些国家进入老龄化社会的变化平行。通过对日本和东亚病例的流行病学和分子病理学比较，我们通过建立以生物学证据为基础的原位癌病理诊断标准，表明口腔浅表癌是一种包括上皮异型增生到微浸润癌的边缘性恶性肿瘤的病变复合体。

项目成果

Gingival metastasis of ovarian carcinoma : report of a case and review of the literature

卵巢癌牙龈转移一例报告并文献复习

• 发表时间: 2009
• 期刊: International Journal of Oral Maxillofacial Surgery 38(10)
• 作者: Yosuke Sato;Akira Suzuki;Shimizu S;Munakata R
• 通讯作者: Munakata R

口腔粘膜組織パラフィン切片伸展のための酢酸処理:上皮のシワ防止

口腔粘膜组织石蜡切片延伸的乙酸处理：预防上皮皱纹

• 发表时间: 2010
• 作者: Shimizu S;Nagai E;Nakamura M;Ueki T;Torata N;Nakashima N;Okamura K;Tanaka M :;Hiroaki Mukaidani;Ahsan MS
• 通讯作者: Ahsan MS

Clinicopathological distinction of two categories of oral squamous cell carcinoma of the tongue: <i>de novo</i> vs. sequential types

两类口腔舌鳞状细胞癌的临床病理学区别：新发型与序贯型

• DOI: 10.3353/omp.16.81
• 发表时间: 2012
• 期刊: Oral Medicine & Pathology
• 作者: Saito M;Kobayashi T;Takagi R;Saku T.
• 通讯作者: Saku T.

Oral cancer in Myanmar: a preliminary survey based on hospital-based cancer registries

• DOI: 10.1111/j.1600-0714.2010.00938.x
• 发表时间: 2011-01-01
• 期刊: JOURNAL OF ORAL PATHOLOGY & MEDICINE
• 影响因子: 3.3
• 作者: Oo, Htun Naing;Myint, Yi Yi;Saku, Takashi
• 通讯作者: Saku, Takashi

口腔扁平上皮癌におけるポドプラニン発現の意義

平足蛋白在口腔鳞状细胞癌中表达的意义

• 发表时间: 2011
• 作者: Masakazu ASAHARA;Masaharu MOTOKAWA;Masayuki Tsuneki;Masayuki Tsuneki;Masayuki Tsuneki;Masayuki Tsuneki;常木雅之;常木雅之
• 通讯作者: 常木雅之