Proteomic analysis of oxidative stress-responsive proteins in metabolic syndrome
Proteomic analysis of oxidative stress-responsive proteins in metabolic syndrome
批准号:
20510192
负责人:
SAKAI Akiko
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
To determine the effects of oxidative stress on metabolic syndrome in vivo, a proteomic analysis was performed in diabetes and control mouse using two-dimensional electrophoresis and MALDI-TOF-TOF-MS. The results showed that differentially expressed proteins with important functions in cellular response to hypoxia were identified compared with normoxia condition. These findings provided new insights into the molecular mechanisms in mediating cellular response to hypoxia.
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Phosphoproteome profiling using a fluorescent phosphosensor dye in two-dimensional polyacrylamide gel electrophoresis.
在二维聚丙烯酰胺凝胶电泳中使用荧光磷酸传感器染料进行磷酸化蛋白质组分析。
DOI:
10.1007/s12010-011-9175-5
发表时间:
2011
期刊:
Appl Biochem Biotechnol
影响因子:
--
作者:
[Otani M, Taniguchi T, Sakai A, et al.]
通讯作者:
et al.
Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice
磷酸传感器染料在人类突变 tau 转基因小鼠蛋白质组学分析中的应用
DOI:
--
发表时间:
2009
期刊:
NeuroReport
影响因子:
1.7
作者:
[M. Takano, M. Otani, Akiko Sakai, K. Kadoyama, S. Matsuyama, Akira Matsumoto, M. Takenokuchi, M. Sumida, T. Taniguchi]
通讯作者:
T. Taniguchi
DOI:
10.1152/ajpheart.91496.2007
发表时间:
2008-05-01
期刊:
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
影响因子:
4.8
作者:
[Hayashi, Tetsuya, Yamashita, Chika, Kitaura, Yasushi]
通讯作者:
Kitaura, Yasushi
DOI:
10.2174/1570161119999990001
发表时间:
2010
期刊:
Current vascular pharmacology
影响因子:
4.5
作者:
[Tetsuya Hayashi;S. Takai;C. Yamashita]
通讯作者:
Tetsuya Hayashi;S. Takai;C. Yamashita
Proteomic analysis of the basic proteins in 5-fluorouracil resistance of human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis.
采用无自由基、高度还原的二维聚丙烯酰胺凝胶电泳方法对人结肠癌细胞系5-氟尿嘧啶耐药中的碱性蛋白进行蛋白质组学分析。
DOI:
--
发表时间:
2008
期刊:
Int. J. Oncol. 33
影响因子:
--
作者:
[Tanaka, S.]
通讯作者:
S.
共 7 条
Regulation of chromatin structure by cohesin in critical period plasticity
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批准号:18K06479
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资助金额:$2.91万
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财政年份:2018
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负责人:SAKAI Akiko
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依托单位:
Elucidation of structure-function relationship of multidrug resistance-associated protein HSPB1 and its clinical application
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资助金额:$3.0万
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财政年份:2017
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负责人:SAKAI Akiko
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依托单位:
Mechanism of neural circuit plasticity investigated from cell-type specific chromatin dynamics of juvenile brain
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批准号:16K14781
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2016
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负责人:SAKAI Akiko
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依托单位:
Studies on the molecular mechanism of 5-fluorouracil response proteins using a proteomic approach
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批准号:23510267
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2011
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负责人:SAKAI Akiko
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依托单位:
A study of practical and effective psychological supports between the early stage after the disaster and the revival stage in the Great East Japan Earthquake
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批准号:22592367
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2010
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负责人:SAKAI Akiko
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依托单位:
Functional analysis of chromatin dynamics during aging by genomic approach
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批准号:22710183
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$3.91万
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财政年份:2010
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负责人:SAKAI Akiko
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依托单位:
Vegetation structure, its dynamics and historical and evolutional backgrounds on unstable terrain with high humidity
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批准号:19570017
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:SAKAI Akiko
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依托单位:
Innovation and evaluation for an educational tool for nursing technique
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批准号:18592348
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.41万
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财政年份:2006
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负责人:SAKAI Akiko
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依托单位:
Tree strategies of sprouting new shoots : why do trees have different ability of sprouting?
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批准号:15570010
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2003
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负责人:SAKAI Akiko
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依托单位:
Analysis of a novel human protein WDC146 highly expressed in testis : for elucidation of the function during spermatogenesis
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批准号:12671602
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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负责人:SAKAI Akiko
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依托单位:
海外基金