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Proteomic analysis of oxidative stress-responsive proteins in metabolic syndrome

Proteomic analysis of oxidative stress-responsive proteins in metabolic syndrome
代谢综合征中氧化应激反应蛋白的蛋白质组学分析
批准号:
20510192
负责人:
SAKAI Akiko
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
To determine the effects of oxidative stress on metabolic syndrome in vivo, a proteomic analysis was performed in diabetes and control mouse using two-dimensional electrophoresis and MALDI-TOF-TOF-MS. The results showed that differentially expressed proteins with important functions in cellular response to hypoxia were identified compared with normoxia condition. These findings provided new insights into the molecular mechanisms in mediating cellular response to hypoxia.
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Phosphoproteome profiling using a fluorescent phosphosensor dye in two-dimensional polyacrylamide gel electrophoresis.
在二维聚丙烯酰胺凝胶电泳中使用荧光磷酸传感器染料进行磷酸化蛋白质组分析。
DOI: 10.1007/s12010-011-9175-5
发表时间: 2011
期刊: Appl Biochem Biotechnol
影响因子: --
作者: [Otani M, Taniguchi T, Sakai A, et al.]
通讯作者: et al.
Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice
磷酸传感器染料在人类突变 tau 转基因小鼠蛋白质组学分析中的应用
DOI: --
发表时间: 2009
期刊: NeuroReport
影响因子: 1.7
作者: [M. Takano, M. Otani, Akiko Sakai, K. Kadoyama, S. Matsuyama, Akira Matsumoto, M. Takenokuchi, M. Sumida, T. Taniguchi]
通讯作者: T. Taniguchi
DOI: 10.1152/ajpheart.91496.2007
发表时间: 2008-05-01
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
影响因子: 4.8
作者: [Hayashi, Tetsuya, Yamashita, Chika, Kitaura, Yasushi]
通讯作者: Kitaura, Yasushi
DOI: 10.2174/1570161119999990001
发表时间: 2010
期刊: Current vascular pharmacology
影响因子: 4.5
作者: [Tetsuya Hayashi;S. Takai;C. Yamashita]
通讯作者: Tetsuya Hayashi;S. Takai;C. Yamashita
7
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    • 批准号:
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      Grant-in-Aid for Scientific Research (C)
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    • 财政年份:
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    • 资助金额:
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    • 财政年份:
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    • 负责人:
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