Molecular mechanism of cyanobacterial circadian clock using the reconstituted in-vitro oscillator.
Molecular mechanism of cyanobacterial circadian clock using the reconstituted in-vitro oscillator.
批准号:
20570035
负责人:
TERAUCHI Kazuki
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The circadian clock can be reconstituted in vitro by the KaiA, KaiB, and KaiC proteins in the presence of ATP. In this study, LdpA presumed to be a redox sensor in cyanobacteria was analyzed biochemically. The structure of the molecule was changed by a redox state. Moreover, it was found that pH of the KaiABC reconstitution system have an effect on the length of the cycle. The two factors, pH in the cell and LdpA, could get involved in the change of the period length the cycle by light.
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シアノバクテリアの生物時計:試験管内で時を刻むタンパク質
蓝藻生物钟:在体外保持时间的蛋白质
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[寺内一姫, 他]
通讯作者:
他
DOI:
10.1101/gad.1661808
发表时间:
2008-06-01
期刊:
GENES & DEVELOPMENT
影响因子:
10.5
作者:
[Kitayama, Yohko, Nishiwaki, Taeko, Kondo, Takao]
通讯作者:
Kondo, Takao
シアノバクテリアで解き明かす体内時計のしくみ
蓝细菌揭示的生物钟机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[寺内一姫, 他]
通讯作者:
他
The Cyanobacterial Clock Protein KaiC ticks in vitro
蓝藻时钟蛋白 KaiC 在体外滴答作响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[寺内一姫, 他]
通讯作者:
他
DOI:
10.1073/pnas.0902587106
发表时间:
2009-08-18
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Ito, Hiroshi, Mutsuda, Michinori, Iwasaki, Hideo]
通讯作者:
Iwasaki, Hideo
共 27 条
In vivo reconstitution of circadian system by heterologously expression of the cyanobacterial Kai proteins
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批准号:23570066
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.49万
-
财政年份:2011
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负责人:TERAUCHI Kazuki
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依托单位:
海外基金