Study on the molecular mechanism of D1 protein aggregation in photosystem II under light and heat stresses

（1）在光、热胁迫下，膜脂过氧化和活性氧的产生是导致D1蛋白氧化损伤、聚集和降解的原因之一。(2)为了防止D1蛋白在光胁迫下进一步受损，类囊体膜显示出包括膜解堆积的结构变化。(3)当光系统II复合物在基粒在强光下受到光损伤时，金属蛋白酶FtsH的亚基在基粒上形成六聚体，可能在基粒边缘，并进行受损的D1蛋白的降解。

The results of our 3 years' research activity are summarized as follows : (1) Under light and heat stresses, lipid peroxidation and the subsequent production of reactive oxygen species take place, which become one of the causes for oxidative damage, aggregation and degradation of the D1 protein. (2) To prevent further damage to the D1 protein under light stess, the thylakoid membranes show structural changes including membrane unstacking. (3) When the photosystem II complexes in the grana are photodamaged under high light, subunits of metalloprotease FtsH forms hexamers at the grana, probably at the grana margin, and carry out degradation of the damaged D1 protein.