Neuroendocrine basis of lunar-synchronized spawning migration in grass puffer

草河豚月球同步产卵迁徙的神经内分泌基础

• 批准号: 20570058
• 负责人: ANDO Hironori
• 金额: $ 3.08万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20570058/
• 关键词: 産卵回遊; 生殖リズム; 松果体; メラトニン; GnRH; キスペプチン; GnIH; 神経ペプチド; メラトニン受容体; クサフグ; 生物リズム; 産卵リズム; 時計遺伝子

To establish molecular basis of neuroendocrine control of lunar-synchronized spawning migration in grass puffer, we assessed changes in magnitudes of gene expression for various neurohormones and their receptors in the hypothalamus and pineal gland. In the hypothalamus, the expressions of those genes significantly increased during the spawning period and showed diurnal and circadian variations in association with changes in expression of melatonin receptor gene. In the pineal gland, melatonin receptor gene showed unique rhythmic expressions with 14 hours cyclicity and monthly variations. Observations of spawning behavior in spawning grounds and in aquarium revealed that the spawning rhythm is endogenously maintained possibly under the control of the circalunar clock in the pineal gland.

为了建立神经内分泌控制的分子基础，月同步产卵迁移在草河豚，我们评估了各种神经激素及其受体在下丘脑和松果体的基因表达的幅度的变化。在下丘脑，这些基因的表达显着增加，在产卵期间，并显示昼夜变化与褪黑激素受体基因的表达变化。松果体中褪黑素受体基因的表达呈现出独特的节律性，以14小时为周期，每月变化。在产卵场和水族箱中对产卵行为的观察表明，产卵节律可能是由松果体中的轮月钟控制的。

项目成果

Dietary Hydroxyproline Improves Collagen Contents of the Fillet in Tiger Puffer (Takifugu rubripes).

膳食羟脯氨酸可提高虎河豚（Takifugu rubripes）鱼片的胶原蛋白含量。

• 发表时间: 2008
• 期刊: Journal of Fish International 3
• 作者: Oikawa;D.;et al.;(他4名)
• 通讯作者: (他4名)

Synchronised Expressions of LPXRFamide Peptide and its Receptor Genes: Seasonal, Diurnal and Circadian Changes During Spawning Period in Grass Puffer

• DOI: 10.1111/j.1365-2826.2010.02081.x
• 发表时间: 2011-01-01
• 期刊: JOURNAL OF NEUROENDOCRINOLOGY
• 影响因子: 3.2
• 作者: Shahjahan, Md.;Ikegami, T.;Ando, H.
• 通讯作者: Ando, H.

Structure of neurohypophysial hormone genes and changes in the levels of expression during spawning season in grass puffer (Takifugu niphobles)

• DOI: 10.1016/j.ygcen.2007.07.009
• 发表时间: 2008-01-15
• 期刊: GENERAL AND COMPARATIVE ENDOCRINOLOGY
• 影响因子: 2.7
• 作者: Mototiashi, Eiji;Hamabata, Tomoko;Ando, Hironorl
• 通讯作者: Ando, Hironorl

Novel bromomelatonin derivatives suppress osteoclastic activity and increase osteoblastic activity: implications for the treatment of bone diseases

• DOI: 10.1111/j.1600-079x.2007.00533.x
• 发表时间: 2008-04
• 期刊: Journal of Pineal Research
• 影响因子: 10.3
• 作者: N. Suzuki;M. Somei;K. Kitamura;R. Reiter;A. Hattori

Quantitative expression analysis of LPXRFa and its receptor genes during the spawning season in grass puffer

草鲀产卵季LPXRFa及其受体基因的定量表达分析

• 发表时间: 2009
• 作者: Shahjahan;Md.;他2名
• 通讯作者: 他2名