Functional role of troponin, a muscle regulatory protein, in non-striated muscle
Functional role of troponin, a muscle regulatory protein, in non-striated muscle
批准号:
20570075
负责人:
OBINATA Takashi
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Troponin has been known as a Ca2+-depedent regulator of muscle contraction characteristic of skeletal and cardiac muscles. In this investigation, we revealed the following. 1) Troponin also plays an essential role in contractile regulation of non-striated muscles such as smooth muscle and myoepithelial cells in ascidian, nematode, and tardigrade (water bear). 2) Troponin of vertebrate and amphioxus (cephalochordate) functions as a brake for muscle contraction in the absence of Ca^<2+>, while troponin in ascidian (urochordate) functions as Ca^<2+>-depedent accelerator for contraction. Based on the functional diversity and evolutionary comparison of troponin molecular structure, we suggest that divergence of troponin occurred during evolution of chordates.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Comparative study of protochordate troponin in the regulation of muscle contraction
原索状肌钙蛋白调节肌肉收缩的比较研究
DOI:
--
发表时间:
2009
期刊:
Proceedings of the 9th International Congress on Cell Biology ICCB2008. Medimond, Italy
影响因子:
--
作者:
[Oshiro K, Dennison J, Tando Y, Sato N, Obinata T]
通讯作者:
Obinata T
Comparative study of protochordate troponin in the regulation of muscle contraction. In "Proceedings of the 9th International Congress on Cell Biology" ICCN 2008
原索状肌钙蛋白调节肌肉收缩的比较研究。
DOI:
--
发表时间:
2008
期刊:
Medimond, Italy
影响因子:
--
作者:
[Ohshiro K, Dennisson J, Tandoh Y, Sato N, Obinata T]
通讯作者:
Obinata T
トロポニンの脊索動物間における構造的類縁関係と機能の多様性
脊索动物肌钙蛋白的结构关系和功能多样性
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Oshiro K, et al., 佐藤成樹, 佐藤成樹, 佐藤成樹, 佐藤成樹, 佐藤成樹]
通讯作者:
佐藤成樹
Functional characteristics of amphioxus troponin in regulation of muscle contraction.
文昌鱼肌钙蛋白调节肌肉收缩的功能特征。
DOI:
--
发表时间:
2010
期刊:
Zoological Science 27
影响因子:
--
作者:
[Dennisson JG, Tando Y, Ogasawara M, Kubokawa K, Sato N, Obinata T]
通讯作者:
Obinata T
Differential expression of two isoforms of myosin-binding protein C in developing chicken cardiac and skeletal muscle cells.
肌球蛋白结合蛋白 C 的两种亚型在发育中的鸡心肌细胞和骨骼肌细胞中的差异表达。
DOI:
--
发表时间:
2010
期刊:
Zoological Science 27
影响因子:
--
作者:
[Saruta K, Obinata T, Sato N]
通讯作者:
Sato N
共 15 条
Regulation of cell motility by troponin, a calcium-regulatory protein.
-
批准号:23570097
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.49万
-
财政年份:2011
-
负责人:OBINATA Takashi
-
依托单位:
An Inventory of Financial Accounting Research in Japan : Under the Changing Circumstances on Accounting Research
-
批准号:21330109
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.98万
-
财政年份:2009
-
负责人:OBINATA Takashi
-
依托单位:
Functional variation of troponin, a muscle regulatory protein, during evolution of chordate animals
-
批准号:17370025
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.82万
-
财政年份:2005
-
负责人:OBINATA Takashi
-
依托单位:
The Rate Regulation and the Relationship between Stock prices and Earnings
-
批准号:15530297
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.77万
-
财政年份:2003
-
负责人:OBINATA Takashi
-
依托单位:
Functional properties of cofilin and C-protein molecules and their roles in formation and maintenance of muscle cellular structure
-
批准号:14340262
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2002
-
负责人:OBINATA Takashi
-
依托单位:
Molecular mechanisms of formation and maintenance of muscle contractile apparatus (myofibrils)
-
批准号:10304065
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$24.02万
-
财政年份:1998
-
负责人:OBINATA Takashi
-
依托单位:
A cell-stretching system as a model system for the study of biomechanics
-
批准号:08558078
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$4.22万
-
财政年份:1996
-
负责人:OBINATA Takashi
-
依托单位:
Role of myosin-binding poteins in myofibrillogenesis
-
批准号:08044191
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$4.86万
-
财政年份:1996
-
负责人:OBINATA Takashi
-
依托单位:
Studies on molecular structure of C-protein and its role in myofibrillogensis
-
批准号:06454024
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.35万
-
财政年份:1994
-
负责人:OBINATA Takashi
-
依托单位:
Actin dynamics and the roles of ADF and cofilin : studies with muscle and nerve as model systems
-
批准号:05044122
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$3.84万
-
财政年份:1993
-
负责人:OBINATA Takashi
-
依托单位:
Molecular mechanisms of myogenesis
-
批准号:03304008
-
项目类别:Grant-in-Aid for Co-operative Research (A)
-
资助金额:$11.2万
-
财政年份:1991
-
负责人:OBINATA Takashi
-
依托单位:
Dynamics of actin assembly during myofibrillogenesis and troponin
-
批准号:03454019
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.16万
-
财政年份:1991
-
负责人:OBINATA Takashi
-
依托单位:
Studies on the regulatory mechanism of myofibril assembly
-
批准号:60440005
-
项目类别:Grant-in-Aid for General Scientific Research (A)
-
资助金额:$13.12万
-
财政年份:1985
-
负责人:OBINATA Takashi
-
依托单位: