Studies on the pathogenic mechanisms of anti-phospholipid antibodies responsible for the thrombotic formation and cell activation.
Studies on the pathogenic mechanisms of anti-phospholipid antibodies responsible for the thrombotic formation and cell activation.
批准号:
20590568
负责人:
NOJIMA Junzo
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The main objective of this study was to clarify the role of anti-phospholipid antibodies (aPL) in the pathogenesis of arterial thromboembolic complications in patients with systemic lupus erythematosus (SLE). Our study demonstrated that aPL cause persistently high TF expression and inflammatory cytokine production in the interaction of monocytes and lymphocytes, which may be an important mechanism for the pathogenesis of arterial thromboembolic complications in SLE patients with APS.
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抗リン脂質抗体症候群と臨床検査
抗磷脂抗体综合征和实验室检查
DOI:
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发表时间:
2010
期刊:
影响因子:
--
作者:
[日高宏哉, 川崎健治, 菅野光俊, 本田孝行, 増田有美子, 野島順三, 野島順三]
通讯作者:
野島順三
抗カルジオリピン抗体,抗プロトロンビン抗体(aPT/PS)測定の問題点:我が国における基準範囲は
抗心磷脂抗体和抗凝血酶原抗体(aPT/PS)测量的问题:日本的参考范围是
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[見谷敦司, 滝脇正貴, 菅野光俊, 川崎健治, 本田孝行, 日高宏哉, 野島順三]
通讯作者:
野島順三
The 99th percentile of anticardiolipin antibodies are lower in Japanese population compared with Caucasian.
与白种人相比,日本人群的 99% 抗心磷脂抗体较低。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[日高宏哉, 滝脇正貴, 見谷敦司, 菅野光俊, 川崎健治, 本田孝行, Masahide Yamazaki]
通讯作者:
Masahide Yamazaki
社会人大学院で行う最先端臨床検査(シンポジウム)
在成人研究生院进行的尖端临床测试(研讨会)
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[滝脇正貴, 見谷敦司, 菅野光俊, 川崎健治, 山内一由, 本田孝行, 日高宏哉, 野島順三]
通讯作者:
野島順三
A first Japanese case of Bartonella henselae induced endocarditis diagnosed by prolonged culture of a specimen from the excised valve
日本首例汉赛巴尔通体引起的心内膜炎,通过对切除瓣膜样本的长期培养进行诊断
DOI:
--
发表时间:
2010
期刊:
Diagnostic Microbiology and Infectious Disease
影响因子:
2.9
作者:
[Tsuneoka H, Yanagihara M, Otani S, Katayama Y, Fujinami H, Nagafuji H, Asari S, Nojima J, Ichihara K]
通讯作者:
Ichihara K
共 33 条
Preparation of diagnostic guidelines for antiphospholipid syndrome and elucidation of the mechanism for arterial and venous thrombosis.
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批准号:18K07468
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:NOJIMA Junzo
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依托单位:
Preparation of guidelines for examination and diagnosis of antiphospholipid syndrome.
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批准号:15K08616
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2015
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负责人:NOJIMA Junzo
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依托单位:
A novel ELISA system for simultaneous detection of six subclasses of anti-phospholipid antibodies for prediction of thrombotic complications among SLE patients with anti-phospholipid syndrome
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批准号:24590696
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:NOJIMA Junzo
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依托单位:
海外基金