The affects of maternal exposure of pesticides on children health : Case-control study based on the large scale cohort of monitoring congenital anomaly

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During 2002 and 2005, 514 pregnant women recruited in Sapporo Toho hospitals, and 29 persistent organochlorine (POC) pesticides from 186 whole blood samples were measured. The concentrations of those chemicals seemed to decline over time (years for blood collection). Maternal age and pre-pregnant body weight were associated with the increased concentrations of those chemicals. In terms of 176 mother-infant pairs, statistical significant associations of maternal POC concentrations and infant birth body size were not found from multi-variable analysis.