Research for the diagnosis and patho physiology of neutrally mediated reflex syncope

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The incidence and characteristics of reflex syncope was investigated, especially its relation between syncope and occupation. The cause of accident during long-distance bus driver was the most common by reflex syncope. In the treatment of reflex syncope, non-pharmacological therapy, especially orthostatic self-traing at home for 30 min. every day was highly effective. The diagnostic pathway, implantable loop recorder was very useful diagnostic tool for syncope patients of unknown origin, and its effect was more useful in the diagnosis of syncope in Japan than in the Europe. Further multicenter studies will be expected near future in Japan.