Diagnosis of unstable angina pectoris by serum deoxyribonuclease I as a new diagnostic maker of myocardial ischemia

在这项研究中，血清dna酶I（DNase I）活性水平在早期可以观察到很高的诊断效能，即使在常规心脏标志物（如肌钙蛋白T或肌酸激酶- mb）水平未升高的不稳定型心绞痛/非ST段抬高型心肌梗死（UAP/NSTEMI）患者中也是如此。血清dna酶I可作为胸痛发作后早期诊断UAP/NSTEMI的有用标志物，无论是否有心肌损伤的证据。

In this study, a high diagnostic efficacy of serum deoxyribonuclease I(DNase I) activity levels could be observed in the early phase, even in unstable angina/non ST segment elevation myocardial infarction(UAP/NSTEMI) patients who did not show elevated levels of conventional cardiac markers, such as troponin T or creatine kinase-MB. The serum DNase I can be a useful marker for the early diagnosis of UAP/NSTEMI after the onset of chest pain, irrespective of the evidence of myocardial injury.