Diagnosis of unstable angina pectoris by serum deoxyribonuclease I as a new diagnostic maker of myocardial ischemia

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In this study, a high diagnostic efficacy of serum deoxyribonuclease I(DNase I) activity levels could be observed in the early phase, even in unstable angina/non ST segment elevation myocardial infarction(UAP/NSTEMI) patients who did not show elevated levels of conventional cardiac markers, such as troponin T or creatine kinase-MB. The serum DNase I can be a useful marker for the early diagnosis of UAP/NSTEMI after the onset of chest pain, irrespective of the evidence of myocardial injury.