A study of the effect that deoxyribonucrease I induces apotosis in cardiac diseases

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We could not find out that deoxyribonuclease I induce apoptosis in cardiac diseases. Then, we evaluated whether nitrotyrosin (NT), a marker of oxidative stress, would elevate after vasospasm induced achtylcholine provocation test in patinets with vasospastic angina pectoris (VSAP). The serum NT levels significantly increased after coronary vasospasm induced by the test, suggensting that serum NT could be a biomarker of transient myocardial ischemia and could contribute to the development of VSAP.