Analysis of chromosomal translocation in humans by using medaka germ cell and its application

染色体易位经常导致多种疾病，如癌症或不孕不育。为了找出一种在人类中频繁发生的易位的机制，我使用了青竹生殖细胞作为模型。此外，我还制作了一个人类细胞系的易位模型系统，并试图寻找与易位有关的因素。因此，我提出了一种新的复发性易位机制。这一结果可能会在未来带来一种新的基因转移技术。

Chromosomal translocations often cause a variety of diseases, such as cancers or infertility. To find mechanism of a frequently occurring translocation in humans as an example, I used medaka germ cells as a model. In addition, I made a translocation model system of a human cell line and made an attempt to find factors involving the translocation. As a result, I proposed a novel mechanism of the recurrent translocation. This result might lead to a new gene transfer technique in the future.