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The role of MLDP in lipid metabolism on lipid droplets.

The role of MLDP in lipid metabolism on lipid droplets.
MLDP 在脂滴脂质代谢中的作用。
批准号:
20770160
负责人:
YAMAGUCHI Tomohiro
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
Lipid droplet (LD), an intracellular storage depot of lipids, is also an active organelle involved in diverse cellular processes, such as membrane traffic and lipid metabolism. Their properties are highly variable among tissues and are possibly determined by the PERILIPIN family of LD-binding proteins. We identified a new member of this family, named MLDP (also called Perilipin 5) and found that it is highly enriched in the heart. MLDP knockout mice completely lacked LDs in the heart, substantiating the essential role of MLDP in keeping heart LDs.
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会议论文
脂肪分解刺激に対する脂肪滴表面タンパク質の応答の解析
脂滴表面蛋白对脂肪分解刺激的响应分析
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [R. L. Ohniwa, K. Morikawa, J. Kim, T. Kobori, K. Hizume, R. Matsumi, H. Atomi, T. Imanaka, T. Ohta, S. H. Yoshimura & K. Takeyasu, 橋本健志]
通讯作者: 橋本健志
DOI: 10.1172/jci34090
发表时间: 2008-08-01
期刊: JOURNAL OF CLINICAL INVESTIGATION
影响因子: 15.9
作者: [Nishino, Naonobu, Tamori, Yoshikazu, Kasuga, Masato]
通讯作者: Kasuga, Masato
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
脂肪滴局在タンパク質PERILIPINファミリーによる脂質代謝制御
脂滴定位蛋白 PERILIPIN 家族对脂质代谢的调节
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Akter MH., Yamaguchi T., Hirose F., Osumi T., Akter MH, Nishino N, 山口智広]
通讯作者: 山口智広
12
    Mechanisms of remodeling of white adipocytes to brown-like adipocytes (browning) in human mesenchymal stem cells.
    The role of lipid droplets in the steroid hormone synthesis in MLTC-1 mouse Leydig tumor cells.
    • 批准号:
      23790098
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.75万
    • 财政年份:
      2011
    • 负责人:
      YAMAGUCHI Tomohiro
    • 依托单位:
    design and evaluation of individual user adaptive recommender system based on awareness
    • 批准号:
      23500197
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2011
    • 负责人:
      YAMAGUCHI Tomohiro
    • 依托单位:
    Development of MBE growth technology of InN-based alloys using quasi-LPE method
    海外基金