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Mechanisms of luteolysis via local GnRH as a follicular developing signal.

Mechanisms of luteolysis via local GnRH as a follicular developing signal.
通过局部 GnRH 作为卵泡发育信号的黄体溶解机制。
批准号:
20780210
负责人:
YONEZAWA Tomohiro
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
Corpora lutea in rats start to regress in the afternoon of diestrus 2. In the present study, metastin and gonadotropin releasing hormone were expressed stage-specifically, which was caused by estrogen from next-developing follicles. These findings could make contributions to avoidance of breeding disorders and fertility treatments.
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会议论文
Differential regulation of phospholipase A(2) activity and prostaglandin E(2) synthesis in activated and non-activated corpora lutea of lactation by the presence and absence of suckling stimulus in rats.
大鼠哺乳刺激存在与否对哺乳期激活和非激活黄体中磷脂酶 A(2) 活性和前列腺素 E(2) 合成的差异调节。
DOI: --
发表时间: 2009
期刊: Prostaglandins Other Lipid Mediat 90
影响因子: --
作者: [Kurusu S, Kamikubo M, Yonezawa T, Kawaminami M]
通讯作者: Kawaminami M
Multiple protective effects of locally administered inhibitors of group IVA phospholipase A2 and cyclooxygenase-2 on pseudopregnant rat corpus luteum from prostaglandin F2α-induced regression.
局部抑制IVA组磷脂酶A2和环加氧酶2对假孕大鼠黄体免受前列腺素F2α诱导的退化的多重保护作用。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kurusu S, Sonoda N, Nakahara M, Yonezawa T, Kawaminami M]
通讯作者: Kawaminami M
ラット性周期黄体に発現するゴナドトロピン放出ホルモンはBaxとBcl-2の発現を制御して黄体のアポトーシスを誘導する
大鼠发情黄体中表达的促性腺激素释放激素调节Bax和Bcl-2的表达并诱导黄体细胞凋亡。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [小形次人, 米澤智洋, 久留主志朗, 汾陽光盛]
通讯作者: 汾陽光盛
Gonadotropin releasing hormone(GnRH)receptor stimulation of Mxl gene expression causes suppression of LRT2 gonadotrope cell growth
促性腺激素释放激素 (GnRH) 受体刺激 Mxl 基因表达导致抑制 LRT2 促性腺细胞生长
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Kawaminami M, et.al.]
通讯作者: et.al.
42
    Regulation of the corpus luteum-life span via alternative splicing of prolactin receptors
    Clarification of local GnRH-induced luteolysis in the rat ovaryand challenge to control thecorpus luteumlife span
    • 批准号:
      22780263
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.58万
    • 财政年份:
      2010
    • 负责人:
      YONEZAWA Tomohiro
    • 依托单位:
    海外基金