Analysis of cytokine secretion and its application using macrophage specific syntaxin 3 knockout mice
Analysis of cytokine secretion and its application using macrophage specific syntaxin 3 knockout mice
巨噬细胞特异性突触蛋白3基因敲除小鼠细胞因子分泌分析及其应用
批准号：
20791063
负责人：
IRIUCHIJIMA Nobuhisa
金额：
$2.66万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2008
资助国家：
日本
项目状态：
已结题
起止时间：
2008 至 2010
中文摘要
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英文摘要
Using macrophage specific syntaxin 3 knockout mice, whether syntaxin 3 was involved in the secretion of TNFα, it was evaluated by staining and ELISA. Unlike the initial estimates,the syntaxin 3 was not found to be involved in the secretion of TNFα. However, syntaxin 3 to move from the Golgi apparatus to the cell periphery, It was thought it is involved in the secretion of other cytokines.
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