Generating Synthetic Anti-HPV18 E7 Peptide
Generating Synthetic Anti-HPV18 E7 Peptide
批准号:
20791167
负责人:
ONO Akiko
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Quantitative binding assay system to investigate the interaction between HPV18 E7 and RB was constructed as expression plasmids. Peptide construct including LxCxE motif showed a certain but labile amount of inhibitory effect .Adjustment of the peptide by adding a pentamerization domain showed stronger inhibitory effect. Cell viability assay did not show significant difference due to poor plasmid transfection efficiency. Adenovirus vectors expressing the pentamerized peptides were constructed for improvement.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
BAC Microarray-CGH法を用いた子宮頸癌のゲノム変化解析
BAC Microarray-CGH法分析宫颈癌基因组变化
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[進伸幸, 市川義一, 末盛友浩, 平沢晃, 阪埜浩司, 青木大輔, 進伸幸, 進伸幸, 進伸幸, 大野暁子]
通讯作者:
大野暁子
Detections of Genomic Alterations in Uterine Cervical Cancer Using BAC Microarray
使用 BAC 微阵列检测宫颈癌的基因组改变
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[進伸幸, 市川義一, 末盛友浩, 平沢晃, 阪埜浩司, 青木大輔, 進伸幸, 進伸幸, 進伸幸, 大野暁子, 大野暁子]
通讯作者:
大野暁子
海外基金