The role of neurogenic inflammation for bacterial translocation

细菌易位是病原体和毒素穿过肠道屏障系统的疾病。这在健康人群中并不常见，但在危重患者中，细菌易位可能会增加发病率和死亡率。我们用脂多糖（LPS）研究了毒素进入肠粘膜的过程。在肠粘膜的特定细胞中观察到LPS。此外，肠道刺激（炎症和扩张）促进了细菌的易位。我们将继续对这一现象进行进一步调查。

Bacterial translocation is the disease that the pathogen and toxins cross the intestinal barrier systems. It is not a frequent event in healthy people, however, in critically ill patients, bacterial translocation may increase the morbidity and mortality. We investigate the ingression of toxin into intestinal mucosa by using a lipopolysaccharide (LPS). LPS was observed in a particular cell at intestinal mucosa. Intestinal stimulations (inflammation and dilation), furthermore, enhance the bacterial translocation. We will continue further investigations about that phenomenon.