Mechanism of periodontal tissue destruction caused by Th17 axis.
Mechanism of periodontal tissue destruction caused by Th17 axis.
批准号:
20791608
负责人:
KOBAYASHI Hiroaki
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
Periodontitis is an inflammatory disease caused by periodontopathic bacteria. The aim of this study was to clarify whether IL-23 production is correlated with periodontal tissue destruction. But, there was no correlation between IL-23 production from periodontitis patients monocytes and clinical parameters. As the severity of periodontitis was not correlated with IL-23 production, individual diversity in IL-23 might not affect the susceptibility of periodontitis directly.
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会议论文
Regulatory roles of β-catenin and AP-1 on osteoprotegerin production in interleukin-1α-stimulated periodontal ligament cells.
β-连环蛋白和 AP-1 对白细胞介素 1α 刺激的牙周膜细胞中骨保护素产生的调节作用。
DOI:
--
发表时间:
2009
期刊:
Yuichi Izumi. Oral Microbiol Immunol 24(5)
影响因子:
--
作者:
[Tomonari Suda, Toshiyuki Nagasawa, Narawat Wara-aswapati, Hiroaki Kobayashi, Kengo Iwasaki, Reiko Yashiro, Doosadee Hormdee, Hiroshi Nitta, Isao Ishikawa]
通讯作者:
Isao Ishikawa
DOI:
10.1111/j.1600-0765.2008.01118.x
发表时间:
2009-06-01
期刊:
JOURNAL OF PERIODONTAL RESEARCH
影响因子:
3.5
作者:
[Bando, Y., Noguchi, K., Izumi, Y.]
通讯作者:
Izumi, Y.
Role of multifunctional matrix protein Thrombospondin-1 in periodontal disease
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