DEVELOPMENT OF THE INFRARED SPECTROSCOPIC METHOD USING INTEGRATING SPHERE OPTICS FOR THE NONINVASIVE QUANTITATIVE EVALUATION OF IMPLANTED CELLS

开发使用积分球光学器件对植入细胞进行无创定量评估的红外光谱方法

• 批准号: 20860052
• 负责人: ISHII Katsunori
• 金额: $ 2.1万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (Start-up)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20860052/
• 关键词: 赤外分光; 分子振動; 積分球; 非侵襲評価; 移植細胞; 再生医療; 幹細胞

Objective of this study is the development of a system can which can measure the optical properties of cells in an infrared wavelength range. In this study, we developed the infrared spectroscopic system with double integrating spheres optics for mid-infrared wavelength region and the sample holder which can determine an accurate thickness of the sample. By using the developed system, the all transmittance spectrum of a mesenchymal stem cell line derived from mouse bone marrow, Kusa-A1, was measured. This technique may achieve to get effective spectroscopic information about cell differentiation and so on, quantitatively.

本研究的目的是开发一种可以在红外波长范围内测量细胞光学特性的系统。在本研究中，我们发展了一套具有双积分球光学系统的中红外光谱系统，以及一套可精确测定样品厚度的样品保持器。利用该系统对小鼠骨髓间充质干细胞株Kusa-A1的全透射光谱进行了测量。该技术可以实现定量地获得细胞分化等有效的光谱信息。

项目成果

Optical properties of laser-treated tissues determined by double-integrating sphere system and inverse Monte Carlo method

双积分球系统和反蒙特卡罗方法测定激光治疗组织的光学特性

• 发表时间: 2009
• 作者: Tatsuya Koyama;Norihiko L. Okamoto;Kyosuke Kishida;Katsushi Tanaka;Haruyuki Inui;Katsunori Ishii
• 通讯作者: Katsunori Ishii

Determination of Optical Property Changes during Laser Therapies

激光治疗过程中光学特性变化的测定

• 发表时间: 2009
• 作者: Norihiko L.Okamoto;Tatsuya Koyama;Kyosuke Kishida;Katsushi Tanaka;Haruyuki Inui;Katsunori Ishii
• 通讯作者: Katsunori Ishii

Inverse Monte Calro法を用いた生体組織の光学定数計測法の開発

开发利用反蒙特卡罗法测量生物组织光学常数的方法

• 发表时间: 2009
• 作者: 中本将嗣;山本高郁;Marko Hamalainen;Lauri Holappa;寺田隆哉
• 通讯作者: 寺田隆哉

Determination of Tissue Optical Properties Using Double Integrating Sphere System for Advanced Laser Medicine

使用双积分球系统测定组织光学特性用于先进激光医学

• 发表时间: 2009
• 作者: Norihiko L.Okamoto;Tatsuya Koyama;Kyosuke Kishida;Katsushi Tanaka;Haruyuki Inui;Katsunori Ishii;弓削是貴;Kunio Awazu
• 通讯作者: Kunio Awazu

Optical properties of laser-treated tissues determined by double-integrating sphere system and inverse Monte Carlo method.

通过双积分球系统和反蒙特卡罗方法测定激光处理组织的光学特性。

• 发表时间: 2009
• 作者: K. Ishii;N. Honda;Y. Kobayashi;T. Nanjo;T. Terada;K. Awazu
• 通讯作者: K. Awazu