课题基金 / 基金详情

Exploration for novel murine hematopoietic stem cells by the use of intra-bone marrow injection methods

Exploration for novel murine hematopoietic stem cells by the use of intra-bone marrow injection methods
骨髓内注射新型小鼠造血干细胞的探索
批准号:
20591158
负责人:
SASAKI Yutaka
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

SASAKI Yutaka的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Intra-bone marrow injection (IBMI) is a powerful method that enables highly efficient hematopoietic stem cell (HSC) engraftment in recipients' bone marrow. Using this method, novel HSCs that are not included in the c-kit^+Sca-1^+Lineage^-(KSL) compartment are explored. IBMI did not detect reproducibly the HSC activity in c-kit^-Sca^-1^+Linfraction, although in some rare cases, long-term hematopoietic reconstitution was observed in the fraction. Therefore, possibility remains that very rare HSCs exist in c-kit-fraction. On the other hand, c-kit^low fraction was proved to contain HSCs in low frequency. These HSCs were characterized.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
マウス造血幹細胞に対するSDF-1の作用機構の解析
SDF-1对小鼠造血干细胞作用机制分析
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [佐々木 豊, 松岡由和, 長谷 真, 薗田精昭]
通讯作者: 薗田精昭
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [窪田哲朗, 福谷泰子, 南木敏宏, 宮坂伸之, 佐々木豊]
通讯作者: 佐々木豊
Marginal expression of CXCR4 on c-kit+Sca-1+Lineage- hematopoietic stem/progenitor cells.
CXCR4 在 c-kit Sca-1 谱系-造血干/祖细胞上的边缘表达。
DOI: --
发表时间: 2009
期刊: International Journal of Hematology. 90(5)
影响因子: --
作者: [Sasaki Y, Matsuoka Y, Hase M, Toyohara T, Murakami M, Takahashi M, Nakatsuka R, Uemura Y, Sonoda Y.]
通讯作者: Sonoda Y.
c-kit発現レベルに基づくマウス骨髄造血幹細胞分画の検討
基于c-kit表达水平的小鼠骨髓造血干细胞分级检测
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [佐々木豊, 松岡由和, 中塚隆介, 植村靖史, 薗田精昭]
通讯作者: 薗田精昭
7
    Scholarly Activities of the Social Science Research Council to Construct the Interdisciplinary Knowledge of the Social Sciences
    • 批准号:
      19K01513
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.41万
    • 财政年份:
      2019
    • 负责人:
      SASAKI Yutaka
    • 依托单位:
    Investigation of c-ktlow murine hematopoietic stem cells for the role in aged animals
    • 批准号:
      25460483
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2013
    • 负责人:
      SASAKI Yutaka
    • 依托单位:
    NMR of extremely diluted impurity helium-3in quantum solid helium-4
    • 批准号:
      22654039
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $1.95万
    • 财政年份:
      2010
    • 负责人:
      SASAKI Yutaka
    • 依托单位:
    Analysis of mechanisms underlying treatment-resistance ofhepatocelluar carcinoma in the point view of post-translationalmodification evaluated by proteomics
    • 批准号:
      21390230
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.4万
    • 财政年份:
      2009
    • 负责人:
      SASAKI Yutaka
    • 依托单位:
    海外基金