Temporal change detection of three dimensional CT images using non-rigid co-registration

本研究的目的是在两次连续CT扫描之间生成减差的CT图像。第一步，我们新开发了DICOM图像数据库，该数据库具有大型且廉价的数据服务器，可以保存大量临床薄层CT数据供研究使用。新服务器存储了30TB以上CT图像数据，三年未发生数据丢失。采用非刚性图像共配软件生成相减图像，但采用非刚性方法对周围解剖结构进行了不完美的共配。更精确的联合登记被认为是临床应用的必要条件。

The purpose of this study was to generate subtracted CT image between two serial CT scans. In the first step, we newly developed a DICOM image database with a large and cheap data server to save a lot of clinical thin slice CT data for research. Over 30TB CT image data were stored in the new server and data loss was not happened for three years. A non-rigid image co-registration software was used for the subtracted image generation, but peripheral anatomy was not perfectly co-registered by the non-rigid method. More precise co-registration was thought to be necessary for the clinical use.