Novel exploitation of hybrid-type armed oncolytic virus for scirrhous gastric cancer
Novel exploitation of hybrid-type armed oncolytic virus for scirrhous gastric cancer
批准号:
20591574
负责人:
NAKAMORI Mikihito
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Scirrhous gastric cancer, a diffusely infiltrating type of poorly differentiated gastric cancer also known as linitis plastic-type cancer is characterized by rapid cancer cell infiltration. Therefore, scirrhous gastric cancer carries a worse prognosis than other types of gastric cancers. Viral therapy for scirrhous gastric cancer is a promising strategy. Viral therapy using herpes simplex virus-1 (HSV-1) is especially practical for clinical application when its safety and therapeutic potency are warranted. We have recently investigated arming oncolytic herpes virus engineered by taxane-mediated molecule.
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DOI:
10.3892/ijo_00000217
发表时间:
2009-04-01
期刊:
INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子:
5.2
作者:
[Ishida, Koichiro, Iwahashi, Makoto, Yamaue, Hiroki]
通讯作者:
Yamaue, Hiroki
様々な機能を付加した抗腫瘍ウイルス療法の開発
开发具有多种功能的抗肿瘤病毒疗法
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[主藤朝也, 三森功士, 横堀武彦, 石丸神矢, 西田尚弘, 古後龍之介, 岩谷岳, 田中文明, 柴田浩平, 藤田博幸, 白水和雄, 森正樹, 中森幹人]
通讯作者:
中森幹人
DOI:
10.1007/s11605-009-1090-5
发表时间:
2010-02-01
期刊:
JOURNAL OF GASTROINTESTINAL SURGERY
影响因子:
3.2
作者:
[Ojima, Toshiyasu, Iwahashi, Makoto, Yamaue, Hiroki]
通讯作者:
Yamaue, Hiroki
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DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Analysis of an arming oncolytic herpes simplex virus in human gastric carcinoma specimen
人胃癌标本中武装溶瘤单纯疱疹病毒的分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[中森幹人, 辻俊明, 岩橋誠, 藤堂具紀, 稲生靖, 山上裕機]
通讯作者:
山上裕機
共 24 条
New development of a selective oncolytic virotherapy for gastric cancer
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批准号:23591946
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:NAKAMORI Mikihito
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依托单位:
Development of molecular therapy targeted for tumor cell and tumor stoma of peritoneal dissemination
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批准号:17591433
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.16万
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财政年份:2005
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负责人:NAKAMORI Mikihito
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依托单位:
海外基金