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Clinicopatological analysis of carcinogenesis of gastric carcinoma

Clinicopatological analysis of carcinogenesis of gastric carcinoma
胃癌发生机制的临床病理学分析
批准号:
20591580
负责人:
SASAKO Mitsuru
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

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中文摘要
翻译
目的探讨胃癌患者的预后及AID/上皮-间充质转化相关基因在胃癌组织中的表达。结果:1.建立了兵库大学胃癌患者数据库,该数据库包含临床因素、病理因素、AID/EMT相关基因的表达。胃癌的临床病理特征是病理异质性和侵袭性。我们对本院切除的胃癌组织进行了AID/EMT(84个基因)的实时定量RT-PCR芯片检测。EMT相关基因与弥漫型肿瘤的侵袭性显著相关。
英文摘要
PurposeWe focused to prognosis of gastric cancer patients, and the expression of AID/Epithelial-mesenchymal transition related gene in gastric cancer tissue.Results1. We established a database of gastric cancer patients in Hyogo Collage of Medicine, which contains clinical factor, pathological factors, the expression of AID/EMT related genes.2. Clinicopathological features of gastric cancer are pathological heterogeneity and invasiveness. We performed quantitative real-time RT-PCR array for AID/EMT (84genes) using resected gastric cancer tissue in our hospital. EMT related gene was significantly related to invasiveness of diffuse type of cancer.
期刊论文(0)
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科研奖励(0)
会议论文
for the Japan Clinical Oncology Group : Functional outcomes after extended surgery for gastric cancer.
日本临床肿瘤学组:胃癌扩大手术后的功能结果。
DOI: --
发表时间: 2011
期刊: British Journal of Surgery 98
影响因子: --
作者: [Y.Kurokawa, M.Sasako, T.Sano, T.Shibata, S.Ito, A.Nashimoto, A.Kurita, T.Kinoshita]
通讯作者: T.Kinoshita
DOI: 10.1038/sj.bjc.6604361
发表时间: 2008-05-20
期刊: British journal of cancer
影响因子: 8.8
作者: [Yoshikawa R, Nakano Y, Tao L, Koishi K, Matsumoto T, Sasako M, Tsujimura T, Hashimoto-Tamaoki T, Fujiwara Y]
通讯作者: Fujiwara Y
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Fujiwara, et al.]
通讯作者: et al.
DOI: 10.1038/sj.bjc.6604806
发表时间: 2009-01-13
期刊: BRITISH JOURNAL OF CANCER
影响因子: 8.8
作者: [Kita, Y., Fukagawa, T., Mori, M.]
通讯作者: Mori, M.
21
    Targeting therapy of Epithelial-Mesenchymal transition about human gastric cancer.
    • 批准号:
      23591949
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2011
    • 负责人:
      SASAKO Mitsuru
    • 依托单位:
    海外基金