Research for signal mechanism of the KIT-positive interstitial cells and development of the new molecular target treatment for the over active bladder
Research for signal mechanism of the KIT-positive interstitial cells and development of the new molecular target treatment for the over active bladder
批准号:
20591886
负责人:
SASAKI Shoichi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
KIT is not only a detection marker of these cells, but also may play a crucial role in the control of bladder function. Research into the effect of c-kit receptor inhibitor, imatinib mesylate, on bladder function implies that KIT-positive ICCs may be therapeutic target cells to reduce bladder overactivity and that the blockage of c-kit receptor may offer a new therapeutic strategy for OAB treatment.
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膀胱排尿筋収縮とNO
膀胱逼尿肌收缩和NO
DOI:
--
发表时间:
2010
期刊:
排尿障害プラクティス Vol.18 No.2
影响因子:
--
作者:
[矢内良昌, 佐々木昌一, 窪田泰江, 橋谷光, 郡健二郎]
通讯作者:
郡健二郎
A kit ligan, stem cell factor as a possible mediator inducing overactive bladder
试剂盒配体、干细胞因子作为诱导膀胱过度活动症的可能介质
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kubota Yasue, Kojima Yoshiyuki, Hayase Masa, Sasaki Shoichi, Kohri Kenjiro]
通讯作者:
Kohri Kenjiro
過活動膀胱におけるイミダフェナシンの有用性の検討
咪达那新在膀胱过度活动症中的有效性检查
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[窪田泰江, 佐々木昌一, 小島祥敬, 早瀬麻沙, 池内隆人, 山田泰之, 石黒良彦, 新美明達, 田貫浩之, 河合徹也, 平尾寛昭, 郡健二郎]
通讯作者:
郡健二郎
中高年女性の尿失禁
中老年女性尿失禁
DOI:
--
发表时间:
2009
期刊:
日本医師会雑誌 138
影响因子:
--
作者:
[窪田泰江, 佐々木昌一, 郡健二郎]
通讯作者:
郡健二郎
クェン酸アルベリンのモルモット膀胱平滑筋に対する作用
枸橼酸艾伯林对豚鼠膀胱平滑肌的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[早瀬麻沙, 橋谷光, 矢内良昌, 窪田泰江, 小島祥敬, 加藤誠, 佐々木昌一, 鈴木光, 郡健二郎]
通讯作者:
郡健二郎
共 49 条
The role of TSP-1 in the pathogenesis of benign prostatic hyperplasia via inflammation.
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批准号:26462451
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2014
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负责人:SASAKI Shoichi
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依托单位:
Exotic hadron-nuclear systems with heavy flavors in lattice QCD
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批准号:23540284
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2011
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负责人:SASAKI Shoichi
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依托单位:
Functional analysis of KIT-positeive interstitial cells for novel strategies of molecular target therapies for benign prostatic hyperplasia
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批准号:23592376
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:SASAKI Shoichi
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依托单位:
Lattice study of hadron structure and strangness contribution
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批准号:19540265
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:SASAKI Shoichi
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依托单位:
Neuropathological study of amyotrophic lateral sclerosis and mutant SOD1 transgenic mice
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批准号:18500280
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.62万
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财政年份:2006
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负责人:SASAKI Shoichi
-
依托单位:
Pathological study of mutant SOD1 (G93A and H46R) transgenic mice
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批准号:14570623
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2002
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负责人:SASAKI Shoichi
-
依托单位:
EAAT1 and EAAT2 immunoreactivity in ALS and pathology of SOD1 (G93A) transgenic mice
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批准号:11670646
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1999
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负责人:SASAKI Shoichi
-
依托单位:
Disturbance of spermatogenesis and apoptosis
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批准号:09470350
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.3万
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财政年份:1997
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负责人:SASAKI Shoichi
-
依托单位:
Study of the proximal axon of anterior horn neurons in amyotrophic lateral sclerosis
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批准号:01570458
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1989
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负责人:SASAKI Shoichi
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依托单位:
海外基金