Basic research on the auto-transplantation of cryopresedved ovarian tissue - Aiming at the quality of life improvement of the young woman cancer patient.
Basic research on the auto-transplantation of cryopresedved ovarian tissue - Aiming at the quality of life improvement of the young woman cancer patient.
批准号:
20591933
负责人:
SUZUKI Nao
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
对于本研究而言,完成旨在作为年轻女性癌症患者治疗缓解后生活质量改善的基础研究成为整个设计。建立了卵巢冷冻组织自体移植新技术;低温保存的最佳方法和自体移植的合适部位。最后,我们在世界上首次成功地从灵长类动物冷冻卵巢(玻璃化)组织的自体移植部分获得受精卵。
英文摘要
As for this study, the accomplishment of the study of the basics that intended the quality of life improvement as the woman after the treatment remission of the young woman cancer patient becomes the whole design. We established the new technology regarding the auto-transplantation of cryopreserved ovarian tissue ; the optimal method of cryopreservation and the appropriate site of auto-transplantation. Finally we succeeded to get the fertilized egg from the auto transplant part of the cryopreserved ovary (vitrification) organization in the primate for the first time in the world.
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Cryopreservation of ovarian tissue was possible after pretreatment with a gonadotropin-releasing hormone agonist.
用促性腺激素释放激素激动剂预处理后,可以冷冻保存卵巢组织。
DOI:
--
发表时间:
2010
期刊:
Reproductive Medicine and Biology
影响因子:
3.4
作者:
[Igarashi S, et al]
通讯作者:
et al
Effects of vitrification solutions and equibiration times on the morphology of cynomolgus ovarian tissues vitrified ultra-rapidly by direct plunging into liquid nitrogen
玻璃化液和平衡时间对液氮超快速玻璃化食蟹猴卵巢组织形态的影响
DOI:
--
发表时间:
2010
期刊:
Reproductive BioMedicine Online
影响因子:
4
作者:
[Hashimoto S, et al]
通讯作者:
et al
卵巣組織凍結の現状とその展望-若年婦人がん患者のQOL向上を目指して
卵巢组织冷冻的现状与展望——旨在提高年轻女性癌症患者的生活质量
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Akitoshi Tsuno, Kaci Nasu, Yukio Kawano, Akitoshi Yuge, Hili Li, Yuri Mase, 鈴木直]
通讯作者:
鈴木直
【シンポジウム】ARTにおける技術革新:若年女性に対する卵巣組織凍結の現状
【研讨会】ART技术创新:年轻女性卵巢组织冷冻现状
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木直, 石塚文平]
通讯作者:
石塚文平
卵子、卵巣凍結保存の現状と展望:若年婦人患者のQOL向上を目指した卵巣組織凍結・自家移植-基礎から臨床へ
卵子和卵巢冷冻保存的现状和前景:旨在提高年轻女性患者生活质量的卵巢组织冷冻和自体移植——从基础到临床实践
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木直, 他]
通讯作者:
他
共 22 条
Innovative Technological Development of Fertility Preservation Treatment Oriented to Improve Cancer Survivorship
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批准号:20H03830
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.4万
-
财政年份:2020
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负责人:SUZUKI Nao
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依托单位:
The research that aims at the establishment of an efficient ovarian tissue cryopreservation and transplantation method - For the young female cancer patients
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批准号:23592421
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2011
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负责人:SUZUKI Nao
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依托单位:
Establishment of molecular targeting therapy against ovarian cancer using human monoclonal antibody
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批准号:17591759
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:SUZUKI Nao
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依托单位:
Analysis of molecular signal transduction pathway between M-CSF and c-fms involved in uterine cervical cancer
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批准号:13671744
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:SUZUKI Nao
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依托单位: