histological investigation of thermosensitivity in the laryngopharynx.

喉咽热敏感性的组织学研究。

• 批准号: 20592017
• 负责人: MIYAKE Naritomo
• 金额: $ 3万
• 依托单位: Tottori University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592017/
• 关键词: 温度受容; 免疫染色; VR1; TRPM8; TRPM5; VRI; 咽喉頭領域; 温度受容体; 咽喉頭; 神経節

It is not investigated in detail about thermosensitivity of laryngopharynx. We guess transiend receptor potential (TRP) family receptors have an intimate involvement in thermosensitivity of laryngopharynx. Most famous receptor is vanilloid receptor type 1(VR1) that is known as capsaicin receptor.We use immunostaining method with VR1, PV5 and PM8 in dorsal root ganglion and trigeminal nerve of Rat. We found VR1 and TRPM positive neuron cell in dorsal root ganglion and trigeminal nerve.

关于咽喉部的温度敏感性还没有详细的研究。推测TRP家族受体与咽喉部的温度敏感性密切相关。辣椒素受体（capsaicin receptor，VR1）是辣椒素受体中最著名的受体之一。在背根神经节和三叉神经内可见VR1和TRPM阳性神经元。

项目成果

三叉神経節、後根神経節におけるTRPチャネルの免疫組織学的検討

三叉神经节和背根神经节TRP通道的免疫组织学研究

• 发表时间: 2011
• 作者: 三宅成智;河本勝之;北野博也
• 通讯作者: 北野博也