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Pharmacological effect of various Prostaglandin analogues on ciliary artery smooth muscle cells

Pharmacological effect of various Prostaglandin analogues on ciliary artery smooth muscle cells
多种前列腺素类似物对睫状动脉平滑肌细胞的药理作用
批准号:
20592070
负责人:
YOSHITOMI Takeshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
Prostaglandin (PG) analogues lower IOP and have been widely used as ocular hypotensive drugs for the treatment of glaucoma. We investigated the effect of this drugs on ocular circulation. Topical PG also increases ocular blood flow measured by the laser speckle method. PG analogues also concentration-dependently relaxed mouse ciliary artery in vitro. This relaxation was also observed in prostanoid FP receptor-deficient mouse ciliary arteries. Thus, we conclude that the PG analogues relaxes ciliary arteries not dependent on prostanoid FP receptors
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眼科研修ノート
眼科培训笔记
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [國方彦志, ほか]
通讯作者: ほか
ラットex vivo網膜標本における急性加圧実験の解析
大鼠离体视网膜制备物急性压力实验分析
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [石川誠, 佐藤徳子, 阿部早苗, 澤田有, 吉冨健志]
通讯作者: 吉冨健志
The effect of acute elevated hydrostatic pressure on the rat ex vivo eyecup preparation, World Glaucoma Congress
急性静水压升高对大鼠离体眼杯制备的影响,世界青光眼大会
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Ishikawa M, Izumi Y, Sato, N, Sawada, Y, Abe S, Yoshitomi T]
通讯作者: Yoshitomi T
Drugs I Cholingergic agents, Medical Treatment of Glaucoma World Glaucoma Association consensus series7
药物 I 胆碱能药物,青光眼的药物治疗 世界青光眼协会共识系列7
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Changwon Kee, Takeshi Yoshitomi, Neeru Gupta]
通讯作者: Neeru Gupta
64
    Pharmacological effect of Neuropeptides on ciliary artery smooth muscle cells
    • 批准号:
      18591908
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.48万
    • 财政年份:
      2006
    • 负责人:
      YOSHITOMI Takeshi
    • 依托单位:
    Vascular effect of various antiglaucoma agent on ciliary artery smooth muscle cells.
    • 批准号:
      15591872
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.24万
    • 财政年份:
      2003
    • 负责人:
      YOSHITOMI Takeshi
    • 依托单位:
    Pharmacological effects of various ant-glaucoma agents on rabbit ciliary artery
    • 批准号:
      12671719
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.98万
    • 财政年份:
      2000
    • 负责人:
      YOSHITOMI Takeshi
    • 依托单位:
    Pharmacological investigation of vascular smooth muscle which affect ocular circulation.
    • 批准号:
      08672032
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $0.7万
    • 财政年份:
      1996
    • 负责人:
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    • 依托单位:
    海外基金