Relationship between glycosylation and virulence of surface proteins from periodontopathic bacterium
Relationship between glycosylation and virulence of surface proteins from periodontopathic bacterium
批准号:
20592165
负责人:
MURAKAMI Yukitaka
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Glycosylated proteins from periodontopathic bacterium Porphyromonas gingivalis were examined by carbohydrate-specific staining and lectin blotting. Major outer membrane proteins RagB and Pgm6/7 as well as other three proteins were identified as glycoproteins. Since mutant strains showed reduced colonization and survival rates, these glycoproteins may be involved in virulence of P. gingivalis.
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Porphyromonas gingivalisの糖蛋白質の同定とそれらの欠失による自己凝集能の検討
牙龈卟啉单胞菌糖蛋白的鉴定及其缺失研究自聚集能力
DOI:
--
发表时间:
2010
期刊:
Bacterial Adherence & Biofilm 24巻
影响因子:
--
作者:
[鈴木久仁博, 小澤幸重, 寒河江登志朗, 山本仁, 太田ルミ, 新美寿英, 太田(横田)ルミ, 鈴木久仁博, 新美寿英, 阿部達彦, 山本 仁, 岸美和子,長谷川義明,村上幸孝,中村洋,吉村文信]
通讯作者:
岸美和子,長谷川義明,村上幸孝,中村洋,吉村文信
歯周病関連細菌Porphyromonas gingivalisのOmpA様糖蛋白質と菌体外マトリックス分子との結合性
牙周病相关细菌牙龈卟啉单胞菌OmpA样糖蛋白与细胞外基质分子的结合特性
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hasegawa, Y, ら, Yoshimura Fら, 村上幸孝,引頭毅,長谷川義明,猪俣恵, 岸美和子,長谷川義明,村上幸孝,中村洋,吉村文信, 村上幸孝,吉村文信]
通讯作者:
村上幸孝,吉村文信
Anchoring and length regulation of Porphyromonas gingivals Mfa1 fimbriae by the downstream gene product Mfa2.
下游基因产物 Mfa2 对牙龈卟啉单胞菌 Mfa1 菌毛的锚定和长度调节。
DOI:
--
发表时间:
2009
期刊:
Microbiology. Vol.155
影响因子:
--
作者:
[Hasegawa Y, Iwami J, Sato K, Park Y, Nishikawa K, Atsumi T, Moriguchi K, Murakami Y, Lamont RJ, Nakamura H, Ohno N, Yoshimura F.]
通讯作者:
Yoshimura F.
Porphyromonas gingivalisの糖蛋白質の同定-欠失株を用いたバイオフィルム形成能および酸化ストレス抵抗性の検討-
牙龈卟啉单胞菌糖蛋白的鉴定 - 使用缺失菌株检查生物膜形成能力和氧化应激抗性 -
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hasegawa, Y, ら, Yoshimura Fら, 村上幸孝,引頭毅,長谷川義明,猪俣恵, 岸美和子,長谷川義明,村上幸孝,中村洋,吉村文信]
通讯作者:
岸美和子,長谷川義明,村上幸孝,中村洋,吉村文信
Anchoring and length regulation of Porphyromonas gingivals Mfal fimbriae by the downstream gene product Mfa2
下游基因产物 Mfa2 对牙龈卟啉单胞菌 Mfal 菌毛的锚定和长度调节
DOI:
--
发表时间:
2009
期刊:
Microbiology Vol.155
影响因子:
--
作者:
[Hasegawa, Y, ら]
通讯作者:
ら
共 12 条
Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation
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批准号:23592720
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
-
财政年份:2011
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负责人:MURAKAMI Yukitaka
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依托单位:
Analysis of major outer membrane proteins from periodontopathogen and relationship between these proteins and clinical symptom in periodontitis
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批准号:15591958
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:MURAKAMI Yukitaka
-
依托单位:
Quantitative analysis fatigue fracture surfaces under Mode II and III and its application to tribology problems
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批准号:11450047
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
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财政年份:1999
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负责人:MURAKAMI Yukitaka
-
依托单位:
Fatigue Mechanism of Superlong Fatigue Failure of steels in Gigacycle Regime
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批准号:08405012
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$20.99万
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财政年份:1996
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负责人:MURAKAMI Yukitaka
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依托单位:
Development of Evaluation System of Mechanical Properties of Multi-Thin Layrs by Ultra-Micro Indentation Test
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批准号:07555351
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$1.28万
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财政年份:1995
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负责人:MURAKAMI Yukitaka
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依托单位:
Application of Fracture Mechanics to Micro and/or Macro Tribology Problem
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批准号:07305050
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$1.73万
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财政年份:1995
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负责人:MURAKAMI Yukitaka
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依托单位:
Direct Observation of the Mechanisms of Fatigue Crack Growth
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批准号:06044275
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项目类别:Grant-in-Aid for Overseas Scientific Survey.
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资助金额:$0.0万
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财政年份:1994
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负责人:MURAKAMI Yukitaka
-
依托单位:
SEM observation of damege mechanism of micro-tribological fracture on hard disk surface
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批准号:04402022
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$19.84万
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财政年份:1992
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负责人:MURAKAMI Yukitaka
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依托单位:
Application of fracture echanics to tribology problems
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批准号:03302029
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项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$9.79万
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财政年份:1991
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负责人:MURAKAMI Yukitaka
-
依托单位:
Development of new high strength Al-Si eutectic alloys and investigation of their fatigue properties in extra-long life range.
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批准号:03555016
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$10.18万
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财政年份:1991
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负责人:MURAKAMI Yukitaka
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依托单位:
Elastic-Plastic Fracture Mechanics Study of Tribology Problems.
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批准号:02452101
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.42万
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财政年份:1990
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负责人:MURAKAMI Yukitaka
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依托单位:
海外基金