Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation
Post-translational modifications of proteins from periodontpathic bacteria: role of glycosylation and phosphorylation
批准号:
23592720
负责人:
MURAKAMI Yukitaka
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
分析了牙周病牙龈卟啉单胞菌的后修饰蛋白。除OmpA样蛋白外,还发现了三种新的糖蛋白,这些糖蛋白与细菌的生长和生物膜的形成有关。使用凝集素柱有效地分离OmpA样蛋白。此外,至少有六个新的磷酸化蛋白进行了鉴定后,使用亲和层析柱分离。
英文摘要
Post-translationally modified proteins from periodontopathic Porphyromonas gingivalis were analyzed. Besides OmpA-like proteins, three novel glycoproteins were found. These glycoproteins were involved in bacterial growth and biofilm formation. OmpA-like proteins were effectively isolated using a lectin column. In addition, at least six novel phosphorylated proteins were identified after separation using an affinity chromatography column.
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Porphyromonas gingivalisのOmpA様蛋白質は細胞毒性の誘導および免疫応答の誘導に関与する
牙龈卟啉单胞菌的 OmpA 样蛋白参与诱导细胞毒性和免疫反应
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[T.Abe, Y.Murakami, K.Nagano, Y.Hasegawa, K.Moriguchi, N.Ohno, K.Shimozato, F.Yoshimura, 田村宗明 他, 出水川雅司,井貝亮太,堀江俊,長谷川義明,川端淳司,北井則行,村上幸孝, Imai K,Victriano AF,Ochiai K,Okamoto T, 長谷川義明,井貝亮太,出水川雅司,堀江俊,永野恵司,吉田康夫,北井則行,村上幸孝,吉村文信, Ann Florence B, 猪俣恵,長谷川義明,村上幸孝]
通讯作者:
猪俣恵,長谷川義明,村上幸孝
DOI:
10.1111/j.2041-1014.2011.00625.x
发表时间:
2011-12-01
期刊:
MOLECULAR ORAL MICROBIOLOGY
影响因子:
3.7
作者:
[Abe, T., Murakami, Y., Yoshimura, F.]
通讯作者:
Yoshimura, F.
Porphyromonas gingivalisのMfa1線毛に付随するMfa3の局在化に関する研究
牙龈卟啉单胞菌Mfa3与Mfa1菌毛相关的定位研究
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Jimi E, Shin M, Furuta H, Tada Y, Kusukawa J, 井貝亮太,長谷川義明,出水川雅司,堀江俊,川端淳司,北井則行,吉村文信,村上幸孝]
通讯作者:
井貝亮太,長谷川義明,出水川雅司,堀江俊,川端淳司,北井則行,吉村文信,村上幸孝
42歯周病関連細菌Porphyromonas gingivalisに存在するリン酸化蛋白質の分離
42 牙周病相关细菌牙龈卟啉单胞菌中磷酸化蛋白的分离
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Matsuo K, Yamamoto N, Morimoto Y, Yamashita Y, Zhang M, Ishikawa A, Tanaka T, Kito S, Takahashi T, 出水川雅司,井貝亮太,堀江俊,長谷川義明,川端淳司,北井則行,村上幸孝]
通讯作者:
出水川雅司,井貝亮太,堀江俊,長谷川義明,川端淳司,北井則行,村上幸孝
歯周病関連細菌Tannerella forsythiaにおけるOmpA様タンパク質の機能に関する研究
牙周病相关菌连翘坦纳菌OmpA样蛋白的功能研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Furuta H, Osawa K, Shin M, Ishikawa A, Matsuo K, Kahn M, Aoki K, Ohya K, Okamoto M, Tominaga K, Takahashi T, Nakanishi O, Jimi E, 村上幸孝,長谷川義明,引頭毅,猪俣恵]
通讯作者:
村上幸孝,長谷川義明,引頭毅,猪俣恵
共 18 条
Relationship between glycosylation and virulence of surface proteins from periodontopathic bacterium
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批准号:20592165
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2008
-
负责人:MURAKAMI Yukitaka
-
依托单位:
Analysis of major outer membrane proteins from periodontopathogen and relationship between these proteins and clinical symptom in periodontitis
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批准号:15591958
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
-
财政年份:2003
-
负责人:MURAKAMI Yukitaka
-
依托单位:
Quantitative analysis fatigue fracture surfaces under Mode II and III and its application to tribology problems
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批准号:11450047
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
-
财政年份:1999
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负责人:MURAKAMI Yukitaka
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依托单位:
Fatigue Mechanism of Superlong Fatigue Failure of steels in Gigacycle Regime
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批准号:08405012
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$20.99万
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财政年份:1996
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负责人:MURAKAMI Yukitaka
-
依托单位:
Development of Evaluation System of Mechanical Properties of Multi-Thin Layrs by Ultra-Micro Indentation Test
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批准号:07555351
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$1.28万
-
财政年份:1995
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负责人:MURAKAMI Yukitaka
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依托单位:
Application of Fracture Mechanics to Micro and/or Macro Tribology Problem
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批准号:07305050
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$1.73万
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财政年份:1995
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负责人:MURAKAMI Yukitaka
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依托单位:
Direct Observation of the Mechanisms of Fatigue Crack Growth
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批准号:06044275
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项目类别:Grant-in-Aid for Overseas Scientific Survey.
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资助金额:$0.0万
-
财政年份:1994
-
负责人:MURAKAMI Yukitaka
-
依托单位:
SEM observation of damege mechanism of micro-tribological fracture on hard disk surface
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批准号:04402022
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项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$19.84万
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财政年份:1992
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负责人:MURAKAMI Yukitaka
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依托单位:
Application of fracture echanics to tribology problems
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批准号:03302029
-
项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$9.79万
-
财政年份:1991
-
负责人:MURAKAMI Yukitaka
-
依托单位:
Development of new high strength Al-Si eutectic alloys and investigation of their fatigue properties in extra-long life range.
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批准号:03555016
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$10.18万
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财政年份:1991
-
负责人:MURAKAMI Yukitaka
-
依托单位:
Elastic-Plastic Fracture Mechanics Study of Tribology Problems.
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批准号:02452101
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.42万
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财政年份:1990
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负责人:MURAKAMI Yukitaka
-
依托单位:
海外基金