Fluorine quantitative measurement in macro area of the tooth using nuclear reaction

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We have developed a new method of quantitative measurement of fluorine in micro area of the tooth by using the nuclear reaction, for the clarification of a quantitative relation between fluorine and carious prevention. Next, we have developed a new method of quantitative measurement of fluorine in macro area of the tooth. By using this method (In-air micro-PIGE and micro-PIXE measurement system), the fluorine distribution all around the cavity was able to be measured for the first time though this area had not been able to be measured by earlier methods. And then the fluorine distribution in the tooth and in the thin layer of material was able to be measured quantitatively at the same time. In addition, it has been shown that the measurement of the fluorine distribution in the carious teeth was also possible. This system may provide future methodologies to clarify the effects of F distribution in the caries process.