Influence of Restoring Occlusal Support with Removable Denture on secretory Immunoglobulin A and nerve growth factor in saliva

活动义齿修复咬合支撑对唾液中分泌性免疫球蛋白A和神经生长因子的影响

• 批准号: 20592295
• 负责人: MAEDA Teruta
• 金额: $ 2.91万
• 依托单位: Osaka Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592295/
• 关键词: 有床義歯補綴学; ストレス; 咬合支持; バイオマーカー; 唾液; 免疫グロブリンA; 神経成長因子; 咬合崩壊; コルチゾール; αアミラーゼ

Salivary stress biomarkers(cortisol, alpha-amylase, secretory immunoglobulin and nerve growth factor) were analyzed in patients without occlusal support in the molar regions. The relationship between before and after restoration by removable partial denture(s)(RPD) was studied. The concentrations of only cortisol and alpha-amylase immediately after treatment for the RPD were significantly higher than those 1 month after treatment. The present data suggest that wearing RPD became a source of stress. However, there were personal variations in concentration of biomarkers with and without RPD. When measuring stress reaction in patients, it is necessary to make various assessments.

唾液应激生物标志物（皮质醇，α-淀粉酶，分泌性免疫球蛋白和神经生长因子）进行了分析，在患者没有咬合支持的磨牙区。目的：研究可摘局部义齿修复前后牙列的关系。仅皮质醇和α-淀粉酶浓度在RPD治疗后即刻显著高于治疗后1个月。目前的数据表明，佩戴RPD成为压力的来源。然而，在有和没有RPD的情况下，生物标志物的浓度存在个体差异。在测量患者的应激反应时，有必要进行各种评估。

项目成果

Stress biomarkers in association with pain discomfort in maxillary palatal mucosa

与上颌腭粘膜疼痛不适相关的应激生物标志物

• 发表时间: 2011
• 作者: Maeda T;Furukawa M;Ito H
• 通讯作者: Ito H

Mechanical stress of short implant placed in the mandibular posterior region under various conditions of daiameter using finite element analysis

有限元分析不同直径条件下下颌后牙区短种植体的机械应力

• 发表时间: 2009
• 作者: 古川麻希子;前田照太;岡崎定司;國場幸恒;古川麻希子;Maeda T
• 通讯作者: Maeda T

How changes in localized pressure under an experimental acrylic plate covering the palatal mucosa affect salivary cortisol concentration and α-amylase activity

覆盖腭粘膜的实验丙烯酸板下局部压力的变化如何影响唾液皮质醇浓度和α-淀粉酶活性

• 发表时间: 2009
• 期刊: J Osaka Dent Univ
• 作者: Ito H;Maeda T;Okazaki J
• 通讯作者: Okazaki J

実験的口蓋床による局部加圧の違いが唾液中コルチゾールおよびアミラーゼ濃度に及ぼす影響

实验腭底局部压力差异对唾液皮质醇和淀粉酶浓度的影响

• 发表时间: 2008
• 作者: Maeda T;Furukawa M;Okazaki J;伊藤秀高;伊藤秀高
• 通讯作者: 伊藤秀高

上顎大連結子の形態と設定位置が唾液中アミラーゼに与える影響

上颌木兰形态和位置对唾液淀粉酶的影响

• 发表时间: 2011
• 作者: 古川麻希子;前田照太;岡崎定司
• 通讯作者: 岡崎定司