A novel diagnostic method of oral inflammation using salivary myeloperoxidase

利用唾液髓过氧化物酶诊断口腔炎症的新方法

• 批准号: 20592445
• 负责人: KANEHIRA Takashi
• 金额: $ 3万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592445/
• 关键词: 唾液; 口腔炎症; ミエロペルオキシダーゼ; スクリーニング; 歯周病; 炎症

We investigated the relationship between salivary myeloperoxidase (MPO) levels and morbidity in periodontal disease. The results revealed that measuring salivary MPO levels was useful for screening for periodontal disease. Our findings further suggested that quantitative analysis of salivary MPO is of value for assessing the efficacy of initial preparation for treatment of periodontal disease and for detecting inflammatory conditions of the oral cavity, including pericoronitis of the wisdom teeth.

我们研究了唾液髓过氧化物酶(MPO)水平与牙周病发病率的关系。结果表明，测定唾液MPO水平可用于牙周病的筛查。我们的研究结果进一步表明，唾液MPO的定量分析对于评估初始制剂治疗牙周病的疗效以及检测包括智齿冠周炎在内的口腔炎症状况具有一定的价值。

项目成果

A pilot study of a simple screening technique for estimation of salivary flow

• DOI: 10.1016/j.tripleo.2009.04.019
• 发表时间: 2009-09-01
• 期刊: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
• 作者: Kanehira, Takashi;Yamaguchi, Tomotaka;Sakamoto, Wataru
• 通讯作者: Sakamoto, Wataru

A pilot study of a simple screening for dry mouth.

口干简单筛查的初步研究。

• 发表时间: 2009
• 期刊: Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108
• 作者: Kanehira T;Yamaguchi T;Takehara J;Kashiwazaki H,Abe T;Morita M;Asano K;Fujii Y;Sakamoto W
• 通讯作者: Sakamoto W

A novel assay system for myeloperoxidase activity in whole saliva

• DOI: 10.1016/j.clinbiochem.2007.12.025
• 发表时间: 2008-05-01
• 期刊: CLINICAL BIOCHEMISTRY
• 影响因子: 2.8
• 作者: Sakamoto, Wataru;Fujii, Yoshihiro;Izumi, Hiroshi
• 通讯作者: Izumi, Hiroshi

口腔内科医として必要な唾液検査

口腔科医生需要进行唾液测试

• 发表时间: 2010
• 作者: Sakamoto W and Kanehira T;et.al.;兼平孝
• 通讯作者: 兼平孝