Efficacy of paroxetine on longitudinal ADL and QOL in post-stroke depression
帕罗西汀对卒中后抑郁症纵向 ADL 和 QOL 的疗效
基本信息
- 批准号:20700455
- 负责人:
- 金额:$ 1.25万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Young Scientists (B)
- 财政年份:2008
- 资助国家:日本
- 起止时间:2008 至 2010
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
We administered paroxetine, one of the selective serotonin reuptake inhibitor (SSRI), or nicergoline as a control to patients with post-stroke depression (PSD) for eight weeks and evaluated the severity of depression, disabilities of stroke and QOL for eight months. The severity of depression was improved at the group which administered paroxetine during a medicine dosage period in comparison with the control group, but did not recognize a difference in ability of gait and ADL at the time of the medicine dosage end. However, it was the tendency that the hospitalization came to shorten in the group which administered paroxetine. The dosage of the SSRI for PSD did not affect longitudinal ADL and QOL. But it improves depression early to diagnose as PSD and administer SSRI, and it may shorten hospitalization.
以选择性5-羟色胺再摄取抑制剂(SSRI)帕罗西汀或尼麦角林为对照,对卒中后抑郁(PSD)患者进行为期8周的抑郁程度、卒中残疾和生活质量评估。与对照组相比,在给药期间给予帕罗西汀的抑郁程度有所改善,但在给药结束时未发现步态能力和日常生活活动能力的差异。而帕罗西汀组的住院时间有缩短的趋势。SSRI治疗PSD的剂量不影响纵向ADL和生活质量。但它可以改善抑郁症的早期诊断为PSD和实施SSRI,并可能缩短住院时间。
项目成果
期刊论文数量(0)
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TAKAHASHI Masanori其他文献
TAKAHASHI Masanori的其他文献
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{{ truncateString('TAKAHASHI Masanori', 18)}}的其他基金
Covert attention using microsaccade as an index in anticipatory response situations of sports
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- 批准号:
17K01689 - 财政年份:2017
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Research on generalized design and intelligence of a self-repairing control system
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- 批准号:
16K06429 - 财政年份:2016
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Role of asymmetric gene expression in projection neurons in the lateral striatum
不对称基因表达在外侧纹状体投射神经元中的作用
- 批准号:
24500373 - 财政年份:2012
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Role of abnormal RNA for the pathophysiology of hereditary muscle diseases
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23591245 - 财政年份:2011
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Effects of the head lift exercise on the pharyngeal pressure of chronic stroke patients with dysphagia
抬头运动对慢性脑卒中吞咽困难患者咽部压力的影响
- 批准号:
23700654 - 财政年份:2011
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Mechanisms of formation and maintenance of signaling center during brain patterning
大脑模式化过程中信号中心的形成和维持机制
- 批准号:
22770206 - 财政年份:2010
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Investigation of the pathomechanism of myotonic syndromes-Na channel disorders of skeletal muscle and myotonic dystrophy
强直性肌强直综合征-骨骼肌Na通道障碍与强直性肌营养不良发病机制的探讨
- 批准号:
20590998 - 财政年份:2008
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
STUDY OF THE PATHOPHYSIOLOGY OF MYOTOIC DYSTROPHY TOWARD THE FUTURE THERAPY FROM THE UNDERSPAND]NG OF MUSCLE WASTING MECHANISM
强直性营养不良的病理生理学研究从了解肌肉萎缩机制走向未来的治疗
- 批准号:
18590938 - 财政年份:2006
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Cryopreservation of periosteum and whole bone by vitrification -establishment of organ freezing program.
玻璃化冷冻保存骨膜和全骨-建立器官冷冻程序。
- 批准号:
14571407 - 财政年份:2002
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
OSTEOGENESIS FROM CRYOPRESERVED PERIOSTEUM- basic studies for tissue and organ cryopreservation
冷冻骨膜成骨——组织和器官冷冻保存的基础研究
- 批准号:
12671441 - 财政年份:2000
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
相似海外基金
難治性神経障害性疼痛に対する塩酸パロキセチン水和物の除痛効果に関する臨床研究
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