Mechanisms of formation and maintenance of signaling center during brain patterning
Mechanisms of formation and maintenance of signaling center during brain patterning
批准号:
22770206
负责人:
TAKAHASHI Masanori
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
In this study, I examined the processes of rhombomere-boundary formation in the Pax6 mutant rat hindbrain. This study suggests that Pax6 may repress neuronal differentiation through Notch signaling pathway in the rhombomere-boundary cells. I also analyzed cell behavior in the hindbrain of EphA4/ephrinB3b double knockdown-zebrafish embryos using high resolution-confocal time-lapse imaging. GFP^+ interface cells at r3/4 boundary abnormally elongated along the A-P axis and then migrated into r4 region, suggesting that EphA4/ephrinB3b signaling is required for sharpening rhombomere boundaries via regulation of cell migration and cell polarity.
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DOI:
10.1038/emboj.2012.43
发表时间:
2012-04-18
期刊:
EMBO JOURNAL
影响因子:
11.4
作者:
[Tsunekawa, Yuji, Britto, Joanne M., Osumi, Noriko]
通讯作者:
Osumi, Noriko
Pax6 regulates rhombomere boundary cell specification in the rat hindbrain
Pax6 调节大鼠后脑菱形边界细胞规范
DOI:
--
发表时间:
2011
期刊:
Mech
影响因子:
--
作者:
[Takahashi, M. and Osumi, N.]
通讯作者:
N.
The Method of Rodent Whole Embryo Culture using the Rotator-type Bottle Culture System.
使用旋转式瓶培养系统进行啮齿动物全胚胎培养的方法。
DOI:
--
发表时间:
2010
期刊:
Journal of Visualized Experiments. 42
影响因子:
--
作者:
[Takahashi, M., Osumi, N.]
通讯作者:
N.
DOI:
10.1016/j.mod.2011.04.001
发表时间:
2011-05
期刊:
Mechanisms of Development
影响因子:
2.6
作者:
[Masanori Takahashi;N. Osumi]
通讯作者:
Masanori Takahashi;N. Osumi
Pax6 is involved in specification of rhombomere boundary cells in the rat hindbrain.
Pax6 参与大鼠后脑菱形边界细胞的规范。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[高橋将文, 大隅典子]
通讯作者:
大隅典子
Covert attention using microsaccade as an index in anticipatory response situations of sports
-
批准号:17K01689
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:TAKAHASHI Masanori
-
依托单位:
Research on generalized design and intelligence of a self-repairing control system
-
批准号:16K06429
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.25万
-
财政年份:2016
-
负责人:TAKAHASHI Masanori
-
依托单位:
Role of asymmetric gene expression in projection neurons in the lateral striatum
-
批准号:24500373
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:TAKAHASHI Masanori
-
依托单位:
Role of abnormal RNA for the pathophysiology of hereditary muscle diseases
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批准号:23591245
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2011
-
负责人:TAKAHASHI Masanori
-
依托单位:
Effects of the head lift exercise on the pharyngeal pressure of chronic stroke patients with dysphagia
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批准号:23700654
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.25万
-
财政年份:2011
-
负责人:TAKAHASHI Masanori
-
依托单位:
Efficacy of paroxetine on longitudinal ADL and QOL in post-stroke depression
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批准号:20700455
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.25万
-
财政年份:2008
-
负责人:TAKAHASHI Masanori
-
依托单位:
Investigation of the pathomechanism of myotonic syndromes-Na channel disorders of skeletal muscle and myotonic dystrophy
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批准号:20590998
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:TAKAHASHI Masanori
-
依托单位:
STUDY OF THE PATHOPHYSIOLOGY OF MYOTOIC DYSTROPHY TOWARD THE FUTURE THERAPY FROM THE UNDERSPAND]NG OF MUSCLE WASTING MECHANISM
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批准号:18590938
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.46万
-
财政年份:2006
-
负责人:TAKAHASHI Masanori
-
依托单位:
Cryopreservation of periosteum and whole bone by vitrification -establishment of organ freezing program.
-
批准号:14571407
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.6万
-
财政年份:2002
-
负责人:TAKAHASHI Masanori
-
依托单位:
OSTEOGENESIS FROM CRYOPRESERVED PERIOSTEUM- basic studies for tissue and organ cryopreservation
-
批准号:12671441
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2000
-
负责人:TAKAHASHI Masanori
-
依托单位:
OSTEOGENESIS FROM CRYOPRESERVED PERIOSTEUM
-
批准号:10671385
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:1998
-
负责人:TAKAHASHI Masanori
-
依托单位:
Development of tissue fixatives to minimize DNA fragmentation - DNA analysis for formalin-fixed and paraffin-embedded tissues -
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批准号:09670451
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.79万
-
财政年份:1997
-
负责人:TAKAHASHI Masanori
-
依托单位:
海外基金