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Mechanisms of formation and maintenance of signaling center during brain patterning

Mechanisms of formation and maintenance of signaling center during brain patterning
大脑模式化过程中信号中心的形成和维持机制
批准号:
22770206
负责人:
TAKAHASHI Masanori
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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英文摘要
In this study, I examined the processes of rhombomere-boundary formation in the Pax6 mutant rat hindbrain. This study suggests that Pax6 may repress neuronal differentiation through Notch signaling pathway in the rhombomere-boundary cells. I also analyzed cell behavior in the hindbrain of EphA4/ephrinB3b double knockdown-zebrafish embryos using high resolution-confocal time-lapse imaging. GFP^+ interface cells at r3/4 boundary abnormally elongated along the A-P axis and then migrated into r4 region, suggesting that EphA4/ephrinB3b signaling is required for sharpening rhombomere boundaries via regulation of cell migration and cell polarity.
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DOI: 10.1038/emboj.2012.43
发表时间: 2012-04-18
期刊: EMBO JOURNAL
影响因子: 11.4
作者: [Tsunekawa, Yuji, Britto, Joanne M., Osumi, Noriko]
通讯作者: Osumi, Noriko
Pax6 regulates rhombomere boundary cell specification in the rat hindbrain
Pax6 调节大鼠后脑菱形边界细胞规范
DOI: --
发表时间: 2011
期刊: Mech
影响因子: --
作者: [Takahashi, M. and Osumi, N.]
通讯作者: N.
The Method of Rodent Whole Embryo Culture using the Rotator-type Bottle Culture System.
使用旋转式瓶培养系统进行啮齿动物全胚胎培养的方法。
DOI: --
发表时间: 2010
期刊: Journal of Visualized Experiments. 42
影响因子: --
作者: [Takahashi, M., Osumi, N.]
通讯作者: N.
DOI: 10.1016/j.mod.2011.04.001
发表时间: 2011-05
期刊: Mechanisms of Development
影响因子: 2.6
作者: [Masanori Takahashi;N. Osumi]
通讯作者: Masanori Takahashi;N. Osumi
Covert attention using microsaccade as an index in anticipatory response situations of sports
  • 批准号:
    17K01689
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.91万
  • 财政年份:
    2017
  • 负责人:
    TAKAHASHI Masanori
  • 依托单位:
Research on generalized design and intelligence of a self-repairing control system
  • 批准号:
    16K06429
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.25万
  • 财政年份:
    2016
  • 负责人:
    TAKAHASHI Masanori
  • 依托单位:
Role of asymmetric gene expression in projection neurons in the lateral striatum
  • 批准号:
    24500373
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.41万
  • 财政年份:
    2012
  • 负责人:
    TAKAHASHI Masanori
  • 依托单位:
Role of abnormal RNA for the pathophysiology of hereditary muscle diseases
  • 批准号:
    23591245
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.24万
  • 财政年份:
    2011
  • 负责人:
    TAKAHASHI Masanori
  • 依托单位:
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