Respiratory and cardiovascular regulations during exercise in hypoxia

缺氧运动时的呼吸和心血管调节

• 批准号: 20700523
• 负责人: KATAYAMA Keisho
• 金额: $ 2.83万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20700523/
• 关键词: 低酸素環境; 運動; 呼吸循環; 低酸素; 呼吸循環応答; 筋交感神経活動; 心拍数; 血圧

The purpose of the present study was to elucidate respiratory and cardiovascular responses at rest and during exercise in hypoxia. Study 1 ; the subjects breathed hypoxic gas mixture (12%O2) for 20 min. Flow-mediated vasodilation (FMD) was measured before and after hypoxic exposure. FMD was increased after acute hypoxia, suggesting that acute hypoxic exposure could improve endothelial function. Study 2 ; the subjects performed cycle exercise at 40% and 70% of maximal exercise intensity in normoxia (21%O2) and hypoxia (12.7%O2). Arterial blood pressure and muscle sympathetic nerve activity during exercise in hypoxia (hypoxic condition) differed from those in normoxia. These results suggest that arterial oxygenation could affect arterial blood pressure regulation during exercise.

本研究的目的是阐明休息和运动期间的呼吸道和心血管反应。研究1;受试者将低氧气体混合物（12％O2）呼吸20分钟。在低氧暴露之前和之后测量流动介导的血管舒张（FMD）。急性缺氧后FMD增加，表明急性低氧暴露可以改善内皮功能。研究2;受试者在常氧（21％O2）和缺氧（12.7％O2）中以40％和70％的最大运动强度进行了循环运动。运动过程中运动过程中动脉血压和肌肉交感神经活性（缺氧状况）与正常氧中的动脉血压和肌肉交感神经活性不同。这些结果表明，动脉氧合可能会影响运动过程中的动脉血压调节。

项目成果

Muscle Deoxygenation during Sustained and Intermittent Isometric Exercise in Hypoxia

• DOI: 10.1249/mss.0b013e3181cae12f
• 发表时间: 2010-07-01
• 期刊: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
• 作者: Katayama, Keisho;Yoshitake, Yasuhide;Ishida, Koji
• 通讯作者: Ishida, Koji

Arterial oxygen delivery and muscle fatigue.(Shinohara M., Advances in neuromuscular physiology of motor skills and muscle fatigue.)

动脉氧输送和肌肉疲劳。（筱原 M.，运动技能和肌肉疲劳的神经肌肉生理学进展。）

• 发表时间: 2009
• 作者: Katayama;K.;Amann M.
• 通讯作者: Amann M.

Effect of the duration of intermittent hypoxia on ventilatory chemosensitivity in humans

间歇性缺氧持续时间对人体通气化疗敏感性的影响

• 发表时间: 2008
• 作者: Katayama;K;et.al.
• 通讯作者: et.al.

運動時の換気応答(宮村実晴編集, 身体トレーニング)

运动时的通气反应（宫村美春编辑，《体能训练》）

• 发表时间: 2009
• 作者: Katayama;K.;Amann M.;片山敬章
• 通讯作者: 片山敬章

Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans

• DOI: 10.1007/s00421-008-0960-y
• 发表时间: 2009-03-01
• 期刊: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
• 影响因子: 3
• 作者: Katayama, Keisho;Ishida, Koji;Miyamura, Miharu
• 通讯作者: Miyamura, Miharu