The improving effect of the redox capacity control upon maintainace hemodialysis patietnts' disability of locomotive function.

首先研究了维生素e包被聚砜膜（VPS-HD）透析对血浆蛋白羰基化的抑制作用。其次，我们使用SF-36评估其对患者健康相关生活质量（HQOL）的影响。VPS-HD抑制血清白蛋白的羰基化，但不提高白蛋白的氧化还原能力。然而，VPS-HD对患者HQOL的身体功能（PF）、身体疼痛（BP）或活力（VT）无显著影响，但显著改善了患者的总体健康感知（GH）。此外，我们发现其对生长激素的改善与对血清白蛋白修饰的抑制之间存在极显著的正相关。这些发现可能表明VPS-HD通过改善患者的氧化还原能力来改善患者的生长激素。

Firstly we investigated inhibition effect of the emodialysis using vitamin E-coated polysulfone membrane(VPS-HD) to the carbonylation of patients' plasma protein. Secondary we evaluated its influence on patients' health-rerated quality of life(HQOL) using SF-36.VPS-HD suppressed the carbonylation of their serum albumin, but not improve albumin's redox capacity. However VPS-HD gave no significant effect to physical functioning(PF), bodily pain(BP) or vitality(VT) of patient's HQOL, it significantly improved general healthy perceptions(GH). In addition, we found marginally significant positive correlation between its improvement of GH and its inhibition for serum albumin modification. These findings may suggest that VPS-HD ameliorates patient's GH throgh patietnt's redox capacity improvement.