课题基金 / 基金详情

Development of a general method for obtaining double KO swine cells which will be used as donors for production of cloned homozygous piglets

Development of a general method for obtaining double KO swine cells which will be used as donors for production of cloned homozygous piglets
开发获得双 KO 猪细胞的通用方法,该细胞将用作生产克隆纯合仔猪的供体
批准号:
21580350
负责人:
SATO Masahiro
金额:
$3.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

SATO Masahiro的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This study aims to develop a general method for obtaining double KO swine cels in which the target gene expression is completely blocked. This was successfully performed by selection of heterogenous KO cels under higher concentrations of selective drugs after repeated delivery of a targeting vector(RDTV). These resulting double KO cells will be used for somatic cell nuclear transfer-mediated production of cloned pigs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Production of genetically modified porcine blastocysts by somatic cell nuclear transfer : preliminary results toward production of xenograft-competent miniature pigs
通过体细胞核移植生产转基因猪囊胚:生产具有异种移植能力的小型猪的初步结果
DOI: --
发表时间: 2010
期刊: J Reprod Dev
影响因子: --
作者: [Himaki T, Watanabe S, Chi H, Yoshida M, Miyoshi K, Sato M]
通讯作者: Sato M
DOI: 10.1111/j.1740-0929.2010.00772.x
发表时间: 2010-01-01
期刊: ANIMAL SCIENCE JOURNAL
影响因子: 2
作者: [Himaki, Takehiro, Yokomine, Taka-aki, Yoshida, Mitsutoshi]
通讯作者: Yoshida, Mitsutoshi
DOI: 10.1111/j.1399-3089.2010.00568.x
发表时间: 2010-01-01
期刊: XENOTRANSPLANTATION
影响因子: 3.9
作者: [Akasaka, Eri, Watanabe, Satoshi, Sato, Masahiro]
通讯作者: Sato, Masahiro
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Otani H, 宇田川潤, 大楠美佐子, 首藤政親, 首藤政親, 谷河麻耶]
通讯作者: 谷河麻耶
28
    Efficient enrichment of homozygous bi-allelic knockout microminiature porcine cells using a novel selection system and production of genome-edited cloned piglets
    • 批准号:
      15K07695
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2015
    • 负责人:
      SATO Masahiro
    • 依托单位:
    Production of cloned genetically modified pigs by a new drug-free gene-modified cell isolation system
    • 批准号:
      24580411
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.58万
    • 财政年份:
      2012
    • 负责人:
      SATO Masahiro
    • 依托单位:
    Methods of characterizing magnetic multi-polar and spin-liquid phases
    Production and analysis of transgenic mice exhibiting concentric hypertrophy in a heart using Cre-loxP system
    • 批准号:
      11470165
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $3.26万
    • 财政年份:
      1999
    • 负责人:
      SATO Masahiro
    • 依托单位:
    海外基金