Development and application of multi-functional hybrid-type organocatalysts based on hypervalent iodine oxidation

摘要研制了一种具有2,2,6,6 -四甲基-1-胡椒酰氧基（TEMPO）和碘苯两个不同催化位点的新型杂合型有机催化剂，并将其应用于醇的氧化反应。两个催化位点以邻苯二甲酸为连接剂，通过酯键连接。在过氧乙酸的存在下，伯醇与催化剂的反应顺利进行，得到相应的羧酸，产率高。

A novel hybrid-type organocatalyst having two deferent catalytic sites, 2, 2, 6, 6-tetramethyl-1-piperidinyloxyl(TEMPO) and iodobenzene sites, was developed and applied the oxidation of alcohols. The two catalytic sites were connected by ester bonds with phthalic acid as a linker. The reaction of primary alcohols with the catalyst in the presence of peracetic acid as a co-oxidant was smoothly proceeded to give the corresponding carboxylic acid in excellent yield.