Studies for the mechanism of the mucosal immunity of mice and the application for desensitization of environmental allergens
Studies for the mechanism of the mucosal immunity of mice and the application for desensitization of environmental allergens
批准号:
21590148
负责人:
TESHIMA Reiko
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We newly obtained following four results in our studies :(1) Increase of IgA production from peyer's patch IgA+B220-cells by addition of culture medium of small-intestinal epithelial cell line MoS13 cells stimulated with TLR1/2 ligand,(2) Decrease of IgE production by yeast glucomannan(YGM)-Fag e 1 conjugates treated mice,(3) Decrease of IL21-production and Tfh cell differentiation by re-stimulated peyer's patch cells obtained from OVA-oral-sensitized BALB/c mice,(4) Identification of T-cell epitopes of major buckwheat allergen Fag e 2.
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Crystallization and preliminary X-ray analysis of a deletion mutant of major buckwheat allergen
主要荞麦过敏原缺失突变体的结晶和初步 X 射线分析
DOI:
--
发表时间:
2009
期刊:
Acta Cryst. F65
影响因子:
--
作者:
[Kezuka Y., Itagaki T., Satoh R., Teshima R., Nonaka T.]
通讯作者:
Nonaka T.
イムノプロテオミクス手法を用いたソバIgE結合タンパク質の網羅的検出
利用免疫蛋白质组学技术全面检测荞麦 IgE 结合蛋白
DOI:
--
发表时间:
2011
期刊:
日本食品化学学会会誌
影响因子:
--
作者:
[佐藤里絵, 中村里香, 手島玲子]
通讯作者:
手島玲子
A convenient and sensitive allergy test : lgE crosslinking-induced luciferase expression in cultured mast cells
方便且灵敏的过敏测试:培养肥大细胞中lgE交联诱导的荧光素酶表达
DOI:
--
发表时间:
2010
期刊:
Allergy
影响因子:
12.4
作者:
[Nakamura R., Uchida Y., Higuchi M., Nakamura R., Teshima R.]
通讯作者:
Teshima R.
ムノプロテオミクス手法を用いたソバIgE結合タンパク質の網羅的検出
使用免疫蛋白质组学技术全面检测荞麦 IgE 结合蛋白
DOI:
--
发表时间:
2011
期刊:
日本食品化学学会会誌
影响因子:
--
作者:
[佐藤里絵, 中村里香, 手島玲子]
通讯作者:
手島玲子
Analysis of T cell epitopes of a major buckwheat allergen, Fag e 2, by using cell-free protein synthesis system
使用无细胞蛋白质合成系统分析主要荞麦过敏原 Fag e 2 的 T 细胞表位
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kimura Y., Katayama S., Teshima R., Akiyama H., Nozawa A., Tozawa T., Nakamura S.]
通讯作者:
Nakamura S.
共 19 条
Analysis of the allergenicity change of structurally modified food allergens and development of highly sensitive detection method
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批准号:24590171
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
-
财政年份:2012
-
负责人:TESHIMA Reiko
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依托单位:
Development of high sensitive analyzing methods for linear- and conformational-epitope of environmental allergens
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批准号:18390043
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.96万
-
财政年份:2006
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负责人:TESHIMA Reiko
-
依托单位:
Study of the effect of environmental chemicals on the high-affinity IgG receptor-mediated signal transudation of mest cells.
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批准号:15590120
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:TESHIMA Reiko
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依托单位:
Study on the mechanism of chemokine release from mast cells by environmental chemicals
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批准号:12672182
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2000
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负责人:TESHIMA Reiko
-
依托单位:
Study of the role of ectokinase on the signal transduction in mast cells
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批准号:09672270
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.79万
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财政年份:1997
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负责人:TESHIMA Reiko
-
依托单位:
Signal transduction in IgE receptor transfected mast cells
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批准号:07672409
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:TESHIMA Reiko
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依托单位:
海外基金