Potential mechanisms responsible for aging promotion derived from the latent national disease, Zn-deficiency

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It has been recently indicated that essential trace elements, particularly zinc deficiency is associated with aging. There are an increase in free radicals, an increase in blood pressure, a reduction in glucose tolerance, the disorder of lipid metabolism and a rise in carcinogenesis in the pathophysiological background of aging. Similar pathophysiology was also observed in zinc deficiency. Thus, the present study indicated that the latent national disease, Zn-deficiency was one of the aging-promoting factors.