Trends in Sudden Cardiac Death and Its Risk Factors in Japan

日本心源性猝死的趋势及其危险因素

• 批准号: 21590731
• 负责人: IMANO Hironori
• 金额: $ 2.91万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21590731/
• 关键词: 心臓突然死; 発症率; 地域住民; 日本人; Nested case-control; 疫学; 前向き研究; コホート研究; Nested case-control研究

This was a population-based longitudinal study. Surveillance of men and women for SCD incidence and risk factors was conducted from 1981 to 2005. The surveyed population was all men and women aged 30-84 years who lived in three rural communities and one urban community(census population about 60, 000) in Japan. In this study, 471 people with SCD were identified over 25 years. Age-adjusted and sex-adjusted incidence of SCD decreased from 1981-85 to 1991-95, and plateaued thereafter. Moreover, the incidence of SCD was so high that a man and age were high.The incidence of SCD was ascertained by systematic surveillance, with 239 cases of SCD identified over this period. For each case of SCD, three control subjects were selected, matched by age, sex, examination year, follow-up time, and community. Hypertension, diabetes mellitus, smoking, major ST-T abnormalities, high amplitude R waves, and increased heart rate(. 77beat/ min) were all independently associated with a 1. 5 to 3. 2-fold increase in SCD risk, while no associations were observed for body mass index(BMI) and hypercholesterolemia.

这是一项基于人群的纵向研究。从1981年到2005年，对男性和女性进行了SCD发病率和危险因素的监测。调查对象为居住在日本3个农村社区和1个城市社区（普查人口约6万人）的30-84岁男女。在这项研究中，在过去的25年里，471名SCD患者被确诊。经年龄和性别调整的SCD发病率从1981-85年到1991-95年下降，此后趋于平稳。此外，SCD的发病率很高，男性和年龄都很高。通过系统监测确定了SCD的发病率，在此期间发现了239例SCD。对于每个SCD病例，选择3名对照受试者，按年龄、性别、检查年份、随访时间和社区匹配。高血压、糖尿病、吸烟、严重ST-T异常、高振幅R波、心率增高(。77beat/ min)均独立与1相关。5比3。SCD风险增加2倍，而体重指数（BMI）和高胆固醇血症没有关联。

项目成果

長期間循環器疾患の疫学調査を実施している地域を対象とした心臓突然死の発症率の推移に関する研究

长期开展心血管病流行病学调查地区心源性猝死发病趋势研究

• 发表时间: 2009
• 作者: 絹田皆子;今野弘規;他
• 通讯作者: 他

The associations of dietary folate, vitamin B6 and B12 intakes with risk of sudden cardiac death : The Circulatory Risk in Communities Study (CIRCS)

膳食叶酸、维生素 B6 和 B12 摄入量与心源性猝死风险的关联：社区循环风险研究 (CIRCS)

• 发表时间: 2011
• 作者: 丸山皆子、今野弘規;他
• 通讯作者: 他

Trends in Sudden Cardiac Death and Risk Factors for Sudden Cardiac death in Japan from 1981 to 2005 : The Circulatory Risk in Communities Study

1981年至2005年日本心脏性猝死的趋势和心脏性猝死的危险因素：社区循环风险研究

• 发表时间: 2010
• 作者: 絹田皆子;今野弘規;他
• 通讯作者: 他

住民健診における非侵襲的検査は心臓突然死を予測するのか

居民健康检查期间的无创检测是否可以预测心源性猝死？

• 发表时间: 2009
• 作者: 大平哲也;今野弘規;他
• 通讯作者: 他

Risk Factors for Sudden Cardiac Death among Japanese : the Circulatory Risk in Communities Study (CIRCS)

日本人心脏性猝死的危险因素：社区循环风险研究 (CIRCS)

• 发表时间: 2012
• 期刊: Journal of Hypertension
• 影响因子: 4.9
• 作者: Ohira T;Maruyama M;Kitamura A;Yamagishi K;Iso H;et al
• 通讯作者: et al