Trends in Sudden Cardiac Death and Its Risk Factors in Japan

这是一项基于人群的纵向研究。从1981年到2005年对男性和女性进行了SCD发病率和危险因素的监测。调查对象为年龄在30-84岁的男性和女性，他们生活在日本的三个农村社区和一个城市社区(人口普查人口约6万)。在这项研究中，471名SCD患者被确认为25年来的患者。年龄调整和性别调整后的SCD发病率从1981-85年下降到1991-95年，此后趋于平稳。此外，SCD的发病率如此之高，以至于一名男子和年龄都很高。SCD的发病率是通过系统监测确定的，在此期间发现了239例SCD。对于每个SCD病例，选择三个对照受试者，按年龄、性别、检查年份、随访时间和社区进行匹配。高血压、糖尿病、吸烟、主要ST-T异常、高幅度R波和心率增加(。而体重指数(BMI)和高胆固醇血症之间没有相关性。

This was a population-based longitudinal study. Surveillance of men and women for SCD incidence and risk factors was conducted from 1981 to 2005. The surveyed population was all men and women aged 30-84 years who lived in three rural communities and one urban community(census population about 60, 000) in Japan. In this study, 471 people with SCD were identified over 25 years. Age-adjusted and sex-adjusted incidence of SCD decreased from 1981-85 to 1991-95, and plateaued thereafter. Moreover, the incidence of SCD was so high that a man and age were high.The incidence of SCD was ascertained by systematic surveillance, with 239 cases of SCD identified over this period. For each case of SCD, three control subjects were selected, matched by age, sex, examination year, follow-up time, and community. Hypertension, diabetes mellitus, smoking, major ST-T abnormalities, high amplitude R waves, and increased heart rate(. 77beat/ min) were all independently associated with a 1. 5 to 3. 2-fold increase in SCD risk, while no associations were observed for body mass index(BMI) and hypercholesterolemia.