Impact of exercise therapy on regression of coronary atherosclerotic plaque

运动疗法对冠状动脉粥样硬化斑块消退的影响

• 批准号: 21590910
• 负责人: DAIDA Hiroyuki
• 金额: $ 2.91万
• 依托单位: Juntendo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21590910/
• 关键词: 急性冠症候群; 血管内超音波; 冠動脈プラーク; 血管リモデリング; 包括的心臓; リハビリテーション; 身体活動量; 急性心筋梗塞; 包括的心臓リハビリテーション; 包括的リハビリテーション

We investigated the effects of comprehensive cardiac rehabilitation (CR) on coronary plaque volume changes and vascular remodeling in patients after acute coronary syndrome (ACS). We enrolled 41 consecutive patients after ACS and patients were divided into the CR (16 patients) and the non-CR group (25 patients). Plaque volume and vascular remodeling were not significantly changed in the two groups during 6 months. However, percent change in plaque volume showed a significant negative correlation with daily physical activity. Intensive physical activity may result in coronary plaque regression in patients after ACS.

我们研究了综合性心脏康复（CR）对急性冠脉综合征（ACS）患者冠状动脉斑块体积变化和血管重构的影响。我们入选了41例ACS后的连续患者，患者分为CR组（16例）和非CR组（25例）。6个月内两组斑块体积和血管重构无明显变化。然而，斑块体积的百分比变化与日常体力活动呈显著负相关。剧烈的体力活动可能导致ACS患者冠状动脉斑块消退。

项目成果

Relationship between advanced glycation end products and plaque progression in patients with acute coronary syndrome: the JAPAN-ACS sub-study.

• DOI: 10.1186/1475-2840-12-5
• 发表时间: 2013-01-07
• 期刊: Cardiovascular diabetology
• 影响因子: 9.3
• 作者: Fukushima Y;Daida H;Morimoto T;Kasai T;Miyauchi K;Yamagishi S;Takeuchi M;Hiro T;Kimura T;Nakagawa Y;Yamagishi M;Ozaki Y;Matsuzaki M;JAPAN-ACS Investigators
• 通讯作者: JAPAN-ACS Investigators

Impact of diabetes on muscle mass, muscle strength, and exercise tolerance in patients after coronary artery bypass grafting

糖尿病对冠状动脉旁路移植术后患者肌肉质量、肌力和运动耐量的影响

• DOI: 10.1016/j.jjcc.2011.05.001
• 发表时间: 2011
• 期刊: J Cardiol
• 影响因子: 2.5
• 作者: Nishitani M;Shimada K;Sunayama S;Masaki Y;Kume A;Fukao K;Sai E;Yamashita H;Ohmura H;Onishi T;Shioya M;Sato H;Shimada A;Yamamoto T;Amano A;Daida H
• 通讯作者: Daida H

Higher Baseline LDL-C Levels Amplify the Short-Term Benefit of Early Intensive Statin Treatment in Acute Coronary Syndrome

• DOI: 10.5551/jat.5587
• 发表时间: 2011-01-01
• 期刊: JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
• 影响因子: 4.4
• 作者: Dohi, Tomotaka;Miyauchi, Katsumi;Daida, Hiroyuki
• 通讯作者: Daida, Hiroyuki

Long-term effect of metabolic syndrome with and without diabetes mellitus on coronary revascularization in Japanese patients undergoing percutaneous coronary intervention

合并或不合并糖尿病的代谢综合征对接受经皮冠状动脉介入治疗的日本患者冠状动脉血运重建的长期影响

• 发表时间: 2011
• 期刊: Clin Cardiol
• 影响因子: 2.7
• 作者: Nishino A.;et al
• 通讯作者: et al

Effects of Aldosterone on coronary plaque volume in hypertensive patients with stable coronary artery disease in ALPS-J subanalysis

ALPS-J亚分析中醛固酮对稳定型冠状动脉疾病高血压患者冠状动脉斑块体积的影响

• 发表时间: 2012
• 作者: Miwa Y;Miyakoshi M;Hoshida K;Yanagisawa R;Abe A;Tsukada T;Ishiguro H;Mera H;Yusu S;Yoshino H;Ikeda T;宮内 克己
• 通讯作者: 宮内 克己