Effects of environmental chemicals on neural development in Tokai High-Avoider(THA) rats
Effects of environmental chemicals on neural development in Tokai High-Avoider(THA) rats
批准号:
21591121
负责人:
YOSHII Fumihito
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
从妊娠第9天到出生后第28天,在THA大鼠的皮肤下注射等量和10倍于普通饲料中的杀菌硫磷。对这些大鼠的后代进行学习能力和行为测试。两组在学习能力上无显著差异。然而,旷场测试表明,杀灭硫磷处理的大鼠的后代存在情绪不稳定。
英文摘要
The same and ten times the amount in a typical diet of Fenitrothion was injected under the skin of THA rats from 9th gestation to the postnatal 28th day. The offspring of these rats were subjected to the learning ability and behavior tests. There was not significant difference in learning ability. However, open-field test indicated that the offspring of Fenitrothion treated rats had an emotional instability.
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DOI:
--
发表时间:
2011
期刊:
Tokai Journal of Experimental and clinical Medicine
影响因子:
--
作者:
[山田晴生, ら, Kondo Y]
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Kondo Y
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DOI:
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发表时间:
2011
期刊:
Ther Res
影响因子:
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DOI:
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发表时间:
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期刊:
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影响因子:
4.1
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通讯作者:
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DOI:
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发表时间:
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期刊:
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影响因子:
6.2
作者:
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DOI:
10.1016/j.expneurol.2011.08.001
发表时间:
2011-11
期刊:
Experimental Neurology
影响因子:
5.3
作者:
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通讯作者:
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共 9 条
A comprehensive analysis of the molecular mechanism supporting high learning ability rats.
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批准号:25430094
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
-
财政年份:2013
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负责人:YOSHII Fumihito
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依托单位:
Gene abnormality and ion-channel change in myotonic dystrophy
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批准号:06670671
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:YOSHII Fumihito
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依托单位:
海外基金